Technologies

Pharmaceuticals & Vitamin D : Pulmonary

Technologies

Treating Pulmonary Disorders with Artificial Lung Surfactant

UW–Madison researchers and others have developed new artificial lung surfactants that mimic the SP-B protein. The materials are based on sequence-random copolymers that contain cationic and lipophilic subunits and are members of the nylon-3 family. They are prepared by ring-opening polymerization of beta-lactams. Also, N-terminal units can be attached to the copolymers to mimic surface tension properties exhibited by the SP-C protein.
P100038US02