Wisconsin Alumni Research Foundation

Technology

Noninvasive Assay for Bovine Embryo Quality

Selection intensity for higher milk production in dairy cattle has contributed to a decline in fertility, posing a challenge to dairy producers. Despite technological advances, the pregnancy rate of c...
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Hasan Khatib, Jenna Kropp | P150131US02

Technology

Blood Protein Biomarkers for Detection of Colon Cancer

Colorectal cancer is a major cause of cancer-related morbidity and mortality in developed nations, causing more than 600,000 deaths worldwide every year. While early detection of localized colorectal ...
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Michael Sussman, William Dove, Melanie Ivancic, Jennifer Pleiman, Edward Huttlin, Perry Pickhardt, Xiaodi Chen, Amy Irving, Adrian Hegeman, Mark Reichelderfer, Gregory Kennedy | P150077US02

Technology

Predicting Glucoregulatory Dysfunction

The term glucoregulatory dysfunction covers a spectrum of disorders from insulin resistance to prediabetes and diabetes. Problems associated with glucoregulatory dysfunction and obesity dominate healt...
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Dhanansayan Shanmuganayagam, Rozalyn Anderson, Ricki Colman, James Ntambi, Mary Lindstrom, Michael Polewski, Maggie Burhans | P150057US02

Technology

Field Test for Mycobacterial Infections

Mycobacterial infections cause major health problems for people and animals, including human tuberculosis, bovine tuberculosis and Johne’s disease. Johne’s disease (or paratuberculosis) afflicts 9...
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Adel Talaat | P150020US02

Technology

Biomarkers for Detecting Prostate Cancer

Prostate cancer is the second most common cancer in American men, causing more than 27,000 deaths every year. An estimated one man in seven will be diagnosed with prostate cancer during his lifetime. ...
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David Jarrard, Bing Yang | P130258US03

Technology

Assay to Determine Risk of Fungal Infection

Fungal infections such as aspergillosis and Valley Fever can be life threatening, particularly in immune-compromised patients. These patients are vulnerable to fungal strains that flourish in hospital...
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Bruce Klein, Marcel Wuethrich | P140236US02

Technology

Detecting Ovarian Cancer and Risk

Ovarian cancer is the most fatal gynecological cancer, killing 15,000 women in the Unites States every year. The overall five-year relative survival rate for women with ovarian cancer is 46 percent. T...
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Halcyon Skinner, Gary Schwartz | P130052US03

Technology

Diagnostic Kit for Blastomycosis

Blastomyces dermatitidis is a soil fungus found throughout the world, and is especially prevalent in the river valleys and Great Lakes region of the United States. If spores are inhaled, blastomycosis...
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Bruce Klein, Theodore Brandhorst | P110280US02

Technology

Early Detection of Hemangiosarcoma and Angiosarcoma

Of the approximately 65 million domestic dogs in the United States, between 1.5 and 2.5 million will contract canine hemangiosarcoma, an incurable tumor of the cells that line blood vessels. Death usu...
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Stuart Helfand, Jaime Modiano | P05078US02

Technology

Prostate Cancer and Melanoma Screening

Almost 200,000 men in the United States develop prostate cancer each year. More than 60,000 people develop melanoma. Early diagnosis is key to survival because the best treatment and prognosis for the...
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Douglas McNeel, Edward Dunphy, Jason Dubovsky, Luke Hoeppner | P06004US

Technology

hMREII Antiserum for the Detection of DNA Damage

DNA damage occurs in organisms as a result of exposure to environmental chemicals and radiation. Failure to repair this damage can lead to tumor formation and cancer. Although a gene has been found in...
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John H. J. Petrini | P95198US

Technology

DNA Encoding a DNA Repair Protein

Nijmegen Breakage Syndrome (NBS) is a rare autosomal recessive disorder characterized by microcephaly, growth retardation, immunodeficiency, higher incidence of cancer, cell cycle defects and radiatio...
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John H. J. Petrini, William Morgan, Richard Maser, James Carney | P98166US

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