The invention provides biheteroaryl dicarboxylates and esters, and salts thereof which are useful generally as modulators of CP4H activity, more particularly as inhibitors of CP4H, or further as chemi...
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Described herein is a mono-end PEGyated functional upstream domain (FUD), pharmaceutical compositions, and its use to inhibit fibrosis such as organ fibrosis, idiopathic pulmonary fibrosis and fibrosi...
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Novel synthetic human scale collagen triple helices assemblies are disclosed. Methods of making self-assembling collagen mimetic peptides that self-assemble into human scale collagen are also disclose...
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Voice impairment (dysphonia) affects an estimated 20 million people in the U.S., resulting in reduced quality of life and direct health care costs exceeding $11 billion per year. Between 60 and 80 per...
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Collagen is the most abundant protein in vertebrates, providing support to virtually every tissue including skin, bone and blood vessel. It is of critical importance in wound healing. Given its signi...
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The global cosmetics industry is a $460 billion dollar market with the skin whitening sector valued at $381 million in 2014. This growing market is projected to increase at a CAGR of 11.7%, reaching $...
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Wound healing is a complex and dynamic process of rebuilding skin and tissue. Chronic or impaired wounds result when tissues fail to progress through the necessary stages of healing. This is a signifi...
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Collagen, the most abundant protein in vertebrates, serves as the fundamental structural protein for vertebrate tissues. Collagen is a fibrous protein consisting of three polypeptide chains that fold ...
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Collagen, the most abundant protein in vertebrates, provides structure for tissues and plays a key role in wound healing. In connective tissue, individual collagen molecules are wound together in tigh...
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Collagen is the most abundant protein in vertebrates. It serves as the fundamental structural protein for vertebrate tissues and is critically important in wound healing. Many diseases, including arth...
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