Technologies

Agriculture

Most Recent Inventions

Soybeans with Increased Resistance to Sclerotinia Stem Rot and Drought Tolerance

UW–Madison researchers have demonstrated that knocking down expression of a specific soybean respiratory burst oxidase homolog protein (GmRBOH-VI) leads to enhanced resistance to S. sclerotiorum and confers drought tolerance.

Using protein sequence similarity searches, the researchers identified seventeen GmRBOHs and studied their contribution to Sclerotinia disease development, drought tolerance and nodulation. Transcript analysis of all seventeen GmRBOHs revealed that out of the six identified groups, group VI (GmRBOH-VI) was specifically and drastically induced following S. sclerotiorum challenge. Virus-induced gene silencing of GMRBOH-VI resulted in enhanced resistance to the fungus and, coincidently, drought stress.

Based on these discoveries, the researchers have developed modified soybeans and production methods available for licensing.
P170294US03

Genetic Testing for Acquired Peripheral Neuropathy in Dogs

UW–Madison researchers have identified a single nucleotide polymorphism (SNP) that is predictive of APN syndrome in dogs, based on a genome-wide association study. Using a population of Labrador retrievers (56 cases and 26 controls), the researchers have shown that a SNP on CFA1 tags the causal variant for APN in the Labrador retriever breed.
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Cranberry Variety Named “Ruby Star” with Consistent High Yield

A UW–Madison researcher has developed a new variety of cranberry known as “Ruby Star.” Ruby Star resulted from a cross between the “HyRed” cranberry (“Stevens” x “Ben Lear #8”) and the “Bergman” cranberry (“Early Black” x “Searles”).

Growers interested in this cranberry variety should license the variety from WARF and obtain vines from one of the approved propagators listed below. The license between WARF and the grower must be in place before vines can be obtained.
  • Cranberry Creek Cranberries Inc.
  • Dempze Cranberry Co.
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Natural Antimicrobial Agent Derived from Biomass

UW–Madison researchers have identified an antimicrobial agent produced as a byproduct of biomass processing. The agent is a diferulate compound called poacic acid (and sometimes also called ‘8-5-DC’). It has been shown to target and destroy the cell walls of several species of fungus and yeast.
P140248US02

Gene Controls Flowering Time in Corn

The researchers now have found a gene in maize that affects flowering time. By modulating this gene, GRMZM2G171650, the onset of flowering in maize may be delayed or accelerated. Standard vector and transgenic methods can be employed to overexpress or suppress the gene, or introduce it into new crop lines.

The gene was identified by studying more than 500 different maize lines. The researchers mapped single nucleotide polymorphisms (SNPs) correlating to early or late flowering traits. A large concentration of such SNPs was located in GRMZM2G171650, a transcription factor on chromosome 3. The gene was of previously unknown function in corn.
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Most Recent Patents

Low-Cost Mastitis Test Speeds Detection

UW–Madison researchers have developed a new test that takes less than two hours and can be used in the field or lab to simultaneously detect the eight most important mastitis pathogens. The assay works on DNA extractions from milk or other samples (e.g., blood or environmental) using loop-mediated isothermal amplification (LAMP) that can be performed using only the kit and a heat block.

The test involves a rapid DNA extraction method (~ 35 minutes) followed by a 47-minute running time. The researchers developed a ‘master mix’ reaction solution for all eight pathogen-specific primers.

The new assay can test for: Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis, E. coli, Klebsiella pneumonia, coagulase-negative Staphylococci and Mycoplasma bovis. The result is a simple yes/no.
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Noninvasive Assay for Bovine Embryo Quality

UW–Madison researchers have identified 11 microRNAs (miRNAs) and 18 mRNAs as indicators of healthy IVF embryo development. They discovered that the miRNAs are differentially expressed between bovine blastocyst-stage embryos and those that fail to develop (‘degenerates’). This is the first report that miRNA levels in the culture medium differ among embryos of different developmental fate and can be used as indicators of embryo viability.
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