Explore WARF Inventions and Patents

WARF Technologies

WARF’s portfolio of more than 1,900 technologies covers a wide range of categories, including analytical instrumentation, pharmaceuticals, food products, agriculture, research tools, medical devices, pluripotent stem cells, clean technology, information technology and semiconductors.

Information summaries, which describe each technology and its applications, benefits, inventors and patent status, can be downloaded, printed and shared by clicking on the technology category links to the left on this page.

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New Inventions

Novel Catalysts for Improved Remediation of Sulfur-Containing Pollutants

A professor of chemistry at the University of Wisconsin-La Crosse has developed a versatile suite of iron-based catalysts with the potential to promote rapid, efficient oxidation of deleterious sulfur-containing compounds present in crude oil, natural gas, and/or aqueous waste streams. With these novel catalysts, there is no need for corrosive base, elevated temperatures, expensive or dangerous oxidants, or high pressures.

Health Monitoring and Imaging System for Concrete Structures

An assistant professor in civil engineering at the University of Wisconsin-Platteville in partnership with an electrical engineer from New Mexico State University, has developed a comprehensive monitoring system capable of identifying interior defects and stress in concrete structures such as bridges. By combining sensor technology with an ultrasound signal generator, multi-channel data acquisition and proprietary data processing algorithms, the interior conditions in any cross section of a bridge can be visualized in 3D. With this technology, small stress changes in the order of 0.1Mpa and cracks as thin as a human hair are detected. Such a combined system provides competitive advantage over existing methods that solely measure stress changes and rely on installation of strain gauges on the surface or inside concrete structures. These methods only provide for measurement of stress changes at the locations where sensors are placed, creating gaps in the evaluation of stress change. In addition, with current technology, holes must be drilled and patched for sensor placement and bridges must be taken out of service during testing. The proposed technology provides for a more absolute evaluation of not only changes in stress but also identification of cracks, does not require drilling of holes and can be used on in-service bridges, saving time, money and providing a more comprehensive assessment of bridge health.

Production of Medium-Chain Fatty Acids from Biorefinery Residue

UW–Madison researchers led by Profs. Daniel Noguera and Timothy Donohue have developed a method for converting unreacted chemical components in stillage to valuable medium-chain fatty acids, such as hexanoic and octanoic acids, using a mixture of microbes (e.g., anaerobic microbiome).

Operationally, a portion of the stillage stream is separated and fed to a bioreactor containing the mixture of microbes, which transforms a fraction of the stillage to MCFAs. The other fraction of the stillage can be sent on to the anaerobic digester to generate electricity (similar to existing biorefineries).

Carbon Nanotube Vacuum Field Emission Transistor Design for Large-Scale Manufacturing

Inventors from the Department of Engineering Physics at the University of Wisconsin-Platteville have created novel transistors by incorporating etched carbon nanotubes into a planar design that is compatible with existing fabrication techniques. In previous studies by others, aligned carbon nanotube transistors have been demonstrated to achieve saturation current that is 1.9 times higher than those that are silicon-based, at an equivalent charge density. In the optimal embodiment of this invention, carbon nanotubes are aligned and feature precise gaps that act as channels to allow the efficient transport of electrons without the need for a vacuum. The anticipated output of this approach will be nanoscale transistors that resist heat and radiation and operate at low voltage and high frequency. To address current challenges with large-scale VFET manufacturing, this technology offers three advantages – the carbon nanotubes can be prefabricated using methods that are already in place, the selective etching process for creating electron channels uses conventional integrated circuit techniques, and the planar design can integrate with existing wafer-based manufacturing methods.

Porous Silicon Nanomembranes for the Rapid Separation of Macromolecules by Size and Shape

Researchers at the University of Wisconsin-Platteville have developed a unique nanomembrane for the separation of biomolecules based on their three-dimensional geometries. These “macromolecular sieves” are produced from laser-etched silicon nanomembranes. The pores in these membranes have openings in the sub-micron range but are designed to significantly reduce the flow impedance of the filtered solution. This design feature allows for faster filtration time when compared with traditional membranes. Nanomembranes with square and rectangular geometries have been produced. Desirable characteristics of the square opening membrane include a high open area of 45% and low standard deviation in opening size (less than 5%). Additionally, the fabricated membranes have been tested with vacuum pumps and show no signs of damage after repeated filtrations with 15 psi of applied pressure differential. Currently, reducing opening size below 100 nm and introducing openings of varying geometries is under development. Further efforts are also underway to decrease the manufacture time and increase the overall scalability of the membrane patterning process.
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New Patents

Modified Yeast to Boost Biofuel Yields

A UW–Madison researcher has developed an S. cerevisiae strain that is 80 percent more effective at fermenting xylose. He discovered that knocking out several genes (hog1, isu1, gre3, ira1/2) enables dramatically faster xylose fermentation under the anaerobic conditions favored by industry.

More Efficient Laminate Analysis

UW–Madison researchers have developed a method for analyzing composite laminate structures that combines the generality of 3-D FEA and efficiency of 2-D FEA whenever it is applicable. The new method works by substituting the laminate layers with much simpler virtual material models having matching characteristics (e.g., overall material properties and relationship between stresses and strains). The updated model can then by analyzed via fully automated 3-D FEA.

The virtual models may be referred to as ABD-equivalent models, as they result in the same ABD stiffness matrices as the real laminate and can act as substitutes if plate-shell assumptions apply.

Analogs of Diptoindonesin G for Breast Cancer Drug Development

UW–Madison researchers have synthesized analogs of Dip G that have shown a greater ability than the parent molecule to decrease ERα expression and stabilize ERβ in cultured breast cancer cells. The compounds are active for ameliorating, attenuating and halting the growth/metastasis of breast cancers.
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