Materials & Chemicals

Most Recent Inventions

Novel Transparent Dilatant Materials Comprised of Single Chemical Component

Research from the University of Wisconsin-Stevens Point has resulted in the synthesis of a series of materials exhibiting a range of dilatant properties. The materials show good transparency and are chemically uniform (e.g. consisting of a single chemical component). The degree of dilatancy is easily controlled by adjusting the compositions of the materials. Due to the range of dilatant properties, good transparency, and single chemical component nature of the dilatant samples, these materials show significant promise for novel uses in protective equipment and other areas related to impact protection, especially where transparency is desirable.

Slippery Liquid-Infused Porous Surfaces (SLIPS) with Improved Antifouling Properties, Small Molecule Release

Building on their work, the researchers have now developed SLIPS capable of preventing adhesion and colonization by bacterial/fungal pathogens, and also killing and/or attenuating non-adherent pathogens in surrounding media. The new approach exploits the polymer and liquid oil phases of the slippery materials to sustain the release of small molecule compounds.

This controlled release approach improves the inherent antifouling properties of SLIPS, has the potential to be general in scope and expands the potential utility of slippery, non-fouling surfaces in diverse contexts.

Perovskites for Stable, High Activity Solid Oxide Fuel Cell Cathodes and Related Technologies

Using high-throughput computing and informatics to screen thousands of candidates, UW–Madison researchers have identified doped perovskite compounds that exhibit both high catalytic activity and thermodynamic stability under ORR operating conditions. These improvements are believed to enable lower-temperature operation of SOFCs and improve device lifetime.

In total, approximately 1950 distinct perovskite compositions were simulated. The most active predicted compounds were found to contain alloys of transition metals and redox-inactive dopant elements (ex., Zr, Hf, Nb, Re and Ta) that can enhance stability.

Nylon-3 Polymers Active Against Clostridium Difficile

UW–Madison researchers and collaborators at Emory Medical School have developed nylon-3 polymers and copolymers active against C. difficile. The polymers have been shown to inhibit outgrowth/growth of the bacteria in spore and vegetative form.

Slippery Antifouling Surfaces with Health, Environmental and Consumer Applications

UW–Madison researchers have developed a new approach for fabricating and functionalizing SLIPS on objects of arbitrary shape, size and topology (e.g., inside a hollow tube, etc.). The new SLIPS have greater control over how fluids behave when they come in contact. For example, they can be designed with oil-free regions to immobilize fluid droplets and/or control how they slide across the surface.

The new SLIPS are antifouling to bacteria, fungi and mammalian cells, and may be used for the controlled release of antibiotics and to prevent thick liquids or dirt from building up on a surface. They are fabricated via the infusion of oils into reactive polymer multilayers.

Most Recent Patents

Generating Medical Isotopes with Safer Vessel and Materials

Wisconsin researchers have developed a ring-shaped, or annular, fissile solution vessel for generating medical isotopes.

The assembly holds three nested chambers. Ions are first directed into an internal target chamber containing a gas. The neutrons that are generated pass outward, through a cooling jacket, into the surrounding fissile solution vessel. This vessel contains an aqueous composition of nuclear material and is shaped to increase heat transfer area to volume. Neutrons strike the nuclear material, generating isotopes and additional neutrons. The solution vessel is separated by another cooling jacket from an outer chamber that reflects neutrons.

Bio-Based Production of Non-Straight-Chain and Oxygenated Fatty Acids for Fuels and More

UW–Madison researchers have identified several enzymes in the bacterium Rhodobacter sphaeroides that can be purified to produce non-straight-chain fatty acids in vitro or expressed in genetically modified microorganisms including E. coli for synthesis in vivo. Strains may be ‘fine-tuned’ to produce a specific type of non-straight-chain fatty acid (e.g., furan-containing) by expressing, overexpressing or deleting the enzymes in various combinations.

New Compounds for Treating High Blood Cholesterol and More

UW–Madison researchers have now developed a method using a rhodium-containing catalyst to make indole compounds, specifically cyclopropyl indoles and cyclohepta[b] indoles. The compounds may be developed into new pharmaceuticals to treat a variety of conditions.