WiSys: T100002US02

Broad Application Bioresorbable Polymers


John Droske, Mark Juetten

OVERVIEWThere is a great need and market opportunity for bioresorbable and biodegradable polymers. These polymers could prove useful in a broad range of applications including health care where the polymers could be used as thermoformed bone adhesives and replacements, stents, drug delivery or low temperature cross linking surgical paste that would minimize necrosis. There is also great demand for biodegradable polymers in packaging applications where degradation time can be selected along with variable rigidity and pliability of the polymer.
THE INVENTIONA researcher at the University of Wisconsin Stevens Point has developed a series of reversible cross linked biocompatible films with straightforward monomer synthesis from mercaptosuccinic acid and succinic acid. Base monomers are polymerized or crosslinked in a highly robust reaction without the need for protection and deprotection allowing for the creation of a wide variety of difunctional and polyfunctional monomers. To date polymers with a wide range of properties have been created, from those that are transparent and flexible to hard and tough polymers. The crosslinking is conducted at a low temperature and little to no lactic acid is needed depending on the application. These crosslinking reactions offer the unique feature of being readily reversible allowing for depolymerized to base monomers without degradation lending the polymers to highly effective recycling for sustainable commodity applications. The monomers can also have application in copolymers and dendrimers.
  • Bioresorbable healthcare applications
  • Biodegradable films and plastics
  • Robust reaction without the need for protection and deprotection
  • Easy selectivity for plastic properties along with degradation time depending on application.
  • Highly recyclable – depolymerization to base monomers without degradation
  • Low temperature polymerization reactions
STAGE OF DEVELOPMENTBase compounds developed
Contact Information
For current licensing status, please contact Jennifer Souter at or (608) 316-4131.
The WiSys Advantage

WiSys Technology Foundation serves the University of Wisconsin System comprehensive campuses by patenting and licensing discoveries to leading companies in Wisconsin, the United States and worldwide. Established in 2000 by the Wisconsin Alumni Research Foundation (WARF) and the UW System, WiSys is building the next generation of patent and licensing opportunities by fostering collaborations among campuses, private research organizations and industry, facilitating high-tech research with grant programs, and promoting student training for employment in a knowledge-based economy. WiSys's income is distributed to the UW campuses, the inventors and their departments to grow future discoveries and educational opportunities.