Technologies

Medical Devices

Most Recent Inventions

Improved System for Stroke Therapy and Rehabilitation

UW-Madison researchers have developed an improved system for stroke therapy and rehabilitation.  This system collects movement intention signals from the brain in real-time via EEG and initiates functional electrical stimulation (FES) of the appropriate muscle(s) to assist the neurons in regrowing their connections from the brain to the muscles along the correct pathways.  Additional general sensory stimulation may be added to this therapy to further encourage proper neuron regrowth. 
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Growth Factor Regulation in Blood Products for Improved Wound Healing

UW–Madison researchers have developed hydrogel microspheres for sequestering problematic growth factors, specifically VEGF, in patient-derived blood products. The degradable microspheres are functionalized with peptide ligands that selectively bind and remove unwanted VEGF from platelet rich plasma and other blood products before they are used in clinical procedures.
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Perivascular Drug Delivery System Inhibits Restenosis

UW–Madison researchers have developed a new device and method for perivascular delivery of drugs to treat and prevent restenosis.

The device consists of a sheath made from a bioresorbable polymer. An anti-proliferative drug is loaded into the sheath. When the sheath is placed around the outside of the blood vessel, the drug is delivered to the vessel over time.
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More Stable Collagen Mimetic Peptides for Wound Healing

UW–Madison researchers have developed a superior linkage between CMP strands that substantially improves their structural stability. The new linkage uses homocysteine in place of cysteine in one of the strands. The resulting bond reduces strain and can therefore be used to enhance CMP-based biomaterials and enable previously inaccessible molecular designs.
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Digital Otoscope for Optimal Access, Visualization

UW–Madison researchers have designed an otoscope featuring a small camera that is mounted on a narrow tip and able to ‘look around’ obstructions such as earwax. The narrow tip also permits other medical instruments to be inserted into the ear while the otoscope is being used (e.g., a curette for removing earwax or foreign objects). A remarkable view of the tympanic membrane is achieved, facilitating proper diagnosis.

Notable features include a disposable, light-conducting speculum sleeve with distal tip smaller than 2 mm. In addition, images may be captured directly from the device and stored in the patient record in compliance with Federal law.
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Most Recent Patents

Implantable Cancer Drug Delivery Device Signals the Future of Personalized Medicine

UW–Madison researchers have developed a new microfluidic device that allows efficient, minimally invasive delivery of drugs within a tumor, sparing patients from the unnecessary drug toxicity of full and indeterminate chemotherapy regimens.

With nothing more than a hypodermic needle, researchers and clinicians are able to administer small implantable devices containing concentrations of chemotherapeutic compounds to the primary tumor. Each device remains anchored and stable by deploying small barbs upon implantation. Specific drugs or drug combinations can be delivered to different areas of the tumor. Surgical removal of the tumor with the devices in place enables assessment of drug efficacy on affected cells.
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Improved Neuron Electrode Array Uses Graphene

UW–Madison researchers have designed a new micro-ECoG device that is flexible and transparent over a broad spectrum. The device includes an implantable electrode array made of conductive graphene sheets on a biocompatible substrate.

Both the substrate and the graphene sheets are transparent over a broad range of wavelengths in the UV, IR and visible spectrum. This allows light to be passed through the array and the underlying tissue for imaging purposes or optical stimulation.

The device is called CLEAR (Carbon Layered Electrode Array).
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Bedside Diagnosis of Swallowing Disorders

UW–Madison researchers have developed software that helps clinicians more easily analyze HRM data. Using a specially adapted manometer inserted through the nasal tract, a series of pressure measurements can be made at different points along the pharynx and esophagus. A computer program uses pattern recognition software to identify changes in pressure when the patient swallows. This data is output as diagnostic values indicating swallowing function.
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