WARF TECHNOLOGIES

Computed tomography (CT) uses special X-ray equipment to obtain image data from different angles of the body and generate a cross-sectional image of body tissues and organs. Because CT is a non-invasive procedure that provides detailed, cross-sectional images of all types of tissue, it is a preferred method for diagnosing diseases of the bowel and colon.

Water or a positive, liquid contrast agent is often administered to help the radiologist better visualize the stomach, small bowel, and colon; however, these agents may not adequately distend the distal small bowel or may take too long to opacify the terminal ileum and cecum in patients suspected of having appendicitis.

UW-Madison researchers have developed improved contrast agents for use during visualization of the gastrointestinal tract during CT scans. The contrast agents include an iso-osmotic contrast agent that preferably comprises polyethylene glycol (PEG) and electrolytes that make the PEG iso-osmotic. A positive contrast agent, such as an iodine- or barium-based contrast agent, may be added to the PEG.

• CT imaging of the gastrointestinal tract

• Rapidly moves through the GI tract, even in the absence of peristalsis
• Decreases the time required to prepare patients for CT scans
• Consistently and rapidly opacifies the terminal ileum and cecum in patients suspected of having appendicitis
• Requires smaller amounts than current contrast agents, reducing cost and improving patient satisfaction
• Provides low attenuation
• Adequately distends the entire small bowel
• Iso-osmotic contrast agent can be administered at the same time as a positive, intravenous contrast agent

Tech Fields

• Medical Imaging : CT