WARF: P03191US

Isotropic Imaging of Vessels with Fat Suppression


Walter Block, Thomas Grist, Aiming Lu

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a technique that doubles the amount of data that can be acquired during any VIPR imaging sequence.
OVERVIEWVastly Under-sampled Isotropic Projection Reconstruction (VIPR) is a magnetic resonance imaging (MRI) data acquisition technique that provides high resolution images at speeds up to 30 times faster than conventional Cartesian methods (see WARF reference number P01008US). By employing VIPR, a team of UW-Madison medical physicists has been able to create high resolution isotropic images of blood vessels during a two-minute scan without the need for a contrast agent. In addition, they have achieved excellent separation of fat and water and extremely short repetition times (TR) by using a radial acquisition. However, because only a single radial line is acquired during each TR, data sampling efficiency and signal-to-noise ratios tend to be low.
THE INVENTIONThe UW-Madison researchers have now extended an eddy current correction method to acquire a second radial line during the rephasing portion of the gradient waveform. Thus, this technology doubles the amount of data that can be acquired during any VIPR imaging sequence, resulting in greatly enhanced signal-to-noise ratios and image sharpness.
  • MRI data acquisition
  • Dampens lipid signals and suppresses fat in MRI images to aid clinical diagnosis
  • Increases data acquisition efficiency, resulting in enhanced signal-to-noise ratios and image sharpness
  • Includes methods that allow signal acquisition throughout the readout gradient without producing significant image artifacts
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For current licensing status, please contact Jeanine Burmania at or 608-960-9846.
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