WARF: P170240US01

Sharpening Filter for Orthovoltage Radiation


Jessica Fagerstrom, Edward Bender, Wesley Culberson, Michael Lawless, Benjamin R. M. Palmer, Larry DeWerd

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a collimator specifically designed for use with orthovoltage radiation to provide a sharper dose profile.

This innovation may enable orthovoltage radiation treatment of neurological tumors at significantly less expense than existing stereotactic radiosurgery systems.
OVERVIEWStereotactic radiosurgery (SRS) is a specialized form of radiation therapy that uses a precise, highly localized photon beam to treat small tumors especially in the brain. Reducing beam energy from the standard megavoltage range to the lower orthovoltage energy range would offer many advantages, including space, cost and dosimetric benefits.
THE INVENTIONUW–Madison researchers have developed a compact filter that increases the sharpness of orthovoltage pencil beams and may be tailored to different beam sizes and focus depths.

The technology features a specially designed collimator and filter disk having concentric circular attenuation regions to produce the necessary sharpening effect. The flat design of the filter disk supports easy installation and replacement, and the concentric circular attenuation regions are amenable to computerized optimization of the region sizes and spacing.
  • For use in medical orthovoltage radiation systems as well as small animal research irradiators to sharpen beam dose delivery
  • Treatment of neurological tumors
  • Installed system likely featuring several different filters, which could be interchanged for a specific radiation treatment plan
  • Improves operation, versatility and manufacturability
  • Filter can be easily installed and removed from collimator block.
  • Provides clinician a wide range of filtration options
Contact Information
For current licensing status, please contact Jeanine Burmania at or 608-960-9846.
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Since its founding in 1925 as the patenting and licensing organization for the University of Wisconsin-Madison, WARF has been working with business and industry to transform university research into products that benefit society. WARF intellectual property managers and licensing staff members are leaders in the field of university-based technology transfer. They are familiar with the intricacies of patenting, have worked with researchers in relevant disciplines, understand industries and markets, and have negotiated innovative licensing strategies to meet the individual needs of business clients.