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WARF: P07324US

  • Assigned to WARF as biological material.

Mouse Monoclonal Antibodies to Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)


INVENTORS -

Richard Burgess, Sarah Duellman, Nancy Thompson, Katherine Mary Foley

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in nine extensively characterized mouse monoclonal antibodies to EBNA-1.
OVERVIEWEpstein-Barr virus (EBV) is one of the most common human viruses and also is associated with some rare cancers. EBV nuclear antigen 1 (EBNA-1) is involved in replication and transcriptional regulation of EBV. EBNA-1 plays an important role in the malignancies associated with EBV infection, including Burkitt’s lymphoma, some Hodgkin’s disease and post-transplant lymphoproliferative diseases. Monoclonal antibodies (mAbs) would be a good tool to characterize EBNA-1; however, few high quality mAbs to EBNA-1 currently exist.
THE INVENTIONUW-Madison researchers have produced nine extensively characterized mouse mAbs to EBNA-1, which provide new tools for studying EBV infection and EBNA-1.
APPLICATIONS
  • Specific molecular recognition of EBNA-1 in vitro or in vivo using experimental techniques such as Western blot, immunoprecipitation (IP) or immunoaffinity chromatography
KEY BENEFITS
  • May lead to the development of new means of detecting and treating EBV infection and associated diseases 
ADDITIONAL INFORMATION
For More Information About the Inventors
Contact Information
For current licensing status, please contact Jennifer Gottwald at jennifer@warf.org or 608-960-9854.
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