Technologies
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WARF: P120130US01

  • Assigned to WARF as biological material.

Reprogrammed Stem Cell Line for Research: IISH3i-CB6


INVENTORS -

Igor Slukvin, Kejin Hu, James Thomson

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a transgene-free iPSC line generated by reprogramming cord blood cells.
OVERVIEWReprogramming blood cells to induced pluripotent stem cells (iPSCs) provides a novel tool for studying blood development in vitro.
THE INVENTIONUW–Madison researchers have developed a reprogrammed iPSC line called IISH3i-CB6. Their method generates iPSCs free of transgene and vector sequences from human bone marrow and cord blood mononuclear cells using non-integrating episomal vectors.
APPLICATIONS
  • Reprogrammed iPSCs for research
KEY BENEFITS
  • Research-grade stem cells
ADDITIONAL INFORMATION
For More Information About the Inventors
Publications
  • Hu K., Yu J., Suknuntha K., et al. 2011. Efficient Generation of Transgene-Free Induced Pluripotent Stem Cells from Normal and Neoplastic Bone Marrow and Cord Blood Mononuclear Cells. Blood. 117, e109–e119.
Contact Information
For current licensing status, please contact Andy DeTienne at adetienne@warf.org or 608-960-9857.
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