Depth-resolved Fluorescence Instrument With Angled Excitation
Inventors: Nirmala Ramanujam, Changfang Zhu, Liu Quan
A fluorescence instrument illuminates the surface of tissue with light of a selected wavelength and light emanating from the tissue due to fluorescence is collected. The angle of illumination of tissue surface and/or collection of fluorescence is changed to probe at various depths beneath the surface of the tissue for a fluorescence layer. Three embodiments of the instrument are described.