Wisconsin Alumni Research Foundation

Pluripotent Stem Cells
Pluripotent Stem Cells
Method Of In Vitro Differentiation Of Neural Stem Cells, Motor Neurons And Dopamine Neurons From Pri
WARF: P07445US

Inventors: Su-Chun Zhang, Xue-jun Li

The Invention
A method of differentiating embryonic stem cells into ventral spinal progenitor cells is disclosed. In one embodiment, the invention comprises culturing a population of cells comprising a majority of cells that are characterized by an early rosette morphology and are Sox1−/Pax6+ in the presence of retinoic acid, wherein the cells express Hoxb4, but not Otx2 or Bf1.
For current licensing status, please contact Andy DeTienne at [javascript protected email address] or 608-960-9857