Wisconsin Alumni Research Foundation

Therapeutics & Vaccines
Therapeutics Vaccines
19-nor-vitamin D Analogs With 1,2-dihydrofuran Ring
WARF: P08399US

Inventors: Hector DeLuca, Katarzyna Sokolowska, Rafal Sicinski, Lori Plum, Margaret Clagett-Dame, Agnieszka Glebocka

The Invention
19-nor-vitamin D analogs having an additional dihydrofuran ring connecting the 1α-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro and in vivo activities, making them therapeutic agents for the treatment or prophylaxis of autoimmune diseases, some types of cancers, secondary hyperparathyroidism, psoriasis, or other skin diseases.
Additional Information
For More Information About the Inventors
For current licensing status, please contact Rafael Diaz at [javascript protected email address] or 608-960-9847