High-Density Nucleic Acid Arrays On Polyester Substrates
Inventors: David Lynn, Matthew Holden, Matthew Carter, Lloyd Smith
Described is a method of synthesizing nucleic acids on polyester substrates and the resulting compositions of matter. The method synthesizes nucleic acids from surface hydroxyl initiation points present on the substrate surface. These surface hydroxyls are present either naturally, or as a result of a chemical treatment to cleave ester bonds on the substrate surface. The preferred polyester substrate contains PET.
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