Research Tools
Thymocyte Humanized Animals, Methods of Making and Methods of Use Thereof
WARF: P230024US02
Inventors: Matthew Brown
The Invention
A UW researcher developed a method for making humanized mice through the transplantation of free neonatal thymus cells into immune deficient mice. The researcher injected 10 million thymocytes, collected from the thymus of neonatal heart surgery patients into the mice. This humanized mouse model can be made using waste product from the surgery. More work needs to be done to characterize the immune system resulting from the injection of these cells into mice, but this model could be a relatively inexpensive option for academic researchers studying T cell development and function.
Additional Information
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Tech Fields
For current licensing status, please contact Jennifer Gottwald at [javascript protected email address] or 608-960-9854