Technologies
PDF


WARF: P140194US01

  • Assigned to WARF as biological material.

Ringworm Fungal Strain for Infection Studies


INVENTORS -

Douglas DeBoer, Karen Moriello

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in UW-8, a strongly fluorescent strain of Microsporum canis used for experimental infection studies in mammals.
OVERVIEWMicrosporum canis is a skin fungal pathogen that causes dermatophytosis (ringworm) most commonly in cats and dogs. Dermatophytosis clinical trials are lengthy and complicated because the nature of the infection can vary. The development of new control measures is greatly facilitated by experimental infection models, in which infections are established and studied in a controlled process.
THE INVENTIONUW–Madison researchers have established that a strain of M. canis, called UW-8, is particularly useful in experimental infection studies. The strain produces a uniquely bright and consistent fluorescence that makes ringworm lesions much easier to identify and measure.

The researchers have used UW-8 for infection studies since 1993, and the attributes of the strain are supported by a body of peer-reviewed literature. UW-8 was selected from natural field strains and can be cultured readily.
APPLICATIONS
  • Experimental infection studies of dermatophytosis
KEY BENEFITS
  • Reproducible and easy to measure infection model
  • In use for more than two decades
STAGE OF DEVELOPMENTThe UW-8 strain has been used since 1993 in multiple published experimental infection studies and studies to determine the efficacy of antifungal treatments.
ADDITIONAL INFORMATION
For More Information About the Inventors
Publications
  • DeBoer D.J. and Moriello K.A. 1994. Development of an Experimental Model of Microsporum Canis Infection in Cats. Vet Microbiol. 42, 289-295.
Contact Information
For current licensing status, please contact Mark Staudt at mstaudt@warf.org or 608-960-9845.
The WARF Advantage

Since its founding in 1925 as the patenting and licensing organization for the University of Wisconsin-Madison, WARF has been working with business and industry to transform university research into products that benefit society. WARF intellectual property managers and licensing staff members are leaders in the field of university-based technology transfer. They are familiar with the intricacies of patenting, have worked with researchers in relevant disciplines, understand industries and markets, and have negotiated innovative licensing strategies to meet the individual needs of business clients.