Explore WARF Inventions and Patents
WARF’s portfolio of more than 1,700 technologies covers a wide range of categories, including analytical instrumentation, pharmaceuticals, food products, agriculture, research tools, medical devices, pluripotent stem cells, clean technology, information technology and semiconductors.
Information summaries, which describe each technology and its applications, benefits, inventors and patent status, can be downloaded, printed and shared by clicking on the technology category links to the left on this page.
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A patient can be given a retinoid or retinoic acid receptor agonist such as all-trans RA (ATRA), 13-cis RA (isotretinoin) or 9-cis RA (alitretinoin). These compounds target the mechanisms that cause sleep apnea in two ways. First, they increase the respiratory drive (urge to breathe). Additionally, they reduce the apneic threshold (the level of CO2 necessary for the induction of breath) to normal levels.
Nutlin-3 is a small molecule MDM2-p53 pathway inhibitor developed in 2004. The researchers use <10x dosage for FXS compared to the dosage used for cancer treatment.
The new design features variable flux linkage characteristics to reduce iron and copper loss under low and high load conditions, respectively. The design does not compromise torque capability and exploits flux leakage already present in every PM machine. In other words, compared to previous IPMs, this technology is able to convert a weakness into an advantage.
More specifically, the rotor geometry is designed such that flux leakage can be shifted to cross the air gap and become desirable flux linkage when stator current is applied. It can be increased or decreased as needed based on load conditions.
For such studies, the ETI larvae are fed test compounds (e.g., from a chemical library) and the functional consequences of the test agent on processes such as neuronal survival, axonal regrowth, and synaptic maintenance are assessed in appropriate assays.