Wisconsin Alumni Research Foundation

Technology

Microbes With Reduced Adhesion Characteristics

This invention from UW Madison researchers presents recombinant microorganisms and methods of using same. The recombinant microorganisms include one or more modifications that reduce the expression an...
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Jan Peter Van Pijkeren, Laura Alexander | P210080US02

Technology

HUMAN BLOOD-BRAIN BARRIER TARGETING ANTIBODIES

UW-Madison researchers have identified new antibodies and related single-chain antibody fragments (scFvs) that bind and transport across the brain vasculature. These promising antibodies were discover...
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Eric Shusta, Charles Stutz, Loukas Goulatis, Julia Georgieva | P200063US02

Technology

RETINAL ORGANOID MODEL SYSTEMS

UW-Madison researchers have developed a retinal organoid model system for evaluating therapies that target genetic mutations. The inventors have discovered that genetic modifications that compromise t...
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David Gamm, Steven Mayerl | P210058US02

Technology

Kras Conditional Knockout Allele

Differentiation of normal stem cells into the correct cell lineage is a tightly controlled process that involves cell-cell and cell-extracellular matrix interactions as well as signaling through cellu...
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Jing Zhang | P210181US01

Technology

Microbial Glycans As A Target Of Human Intelectin

The present disclosure provides for methods of diagnosing and treating bacterial infections. Human Intelectin 1 (hIntL-1) has been shown to bind selectively to glycan components on bacteria including ...
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Laura Kiessling, Darryl Wesener, Kittikhun Wangkanont | P150027US02

WARF