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55 Results for 'Vaccines'
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Technology
Improved Production of Influenza Virus, Including H1N1, for Vaccine Manufacture
The H1N1 influenza virus, known as the “swine flu,” has been declared a pandemic. While this virus is less virulent than many circulating strains of flu virus, it has become the subject of signi...
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Yoshihiro Kawaoka, Taisuke Horimoto, Shin Murakami | P100078US02
Technology
Attenuated Influenza Viruses for Development of Live Influenza Vaccine
Influenza is a major disease in humans that can be prevented by vaccination. Because new epidemic strains arise every year or two, influenza vaccines must be adapted almost every year. Live attenuat...
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Yoshihiro Kawaoka, Hatice Akarsu, Kiyoko Horimoto | P09022US02
Technology
Cell Line for Evaluating Influenza Virus Sensitivity to NA Inhibitors
The extensive use of neuraminidase (NA) inhibitors to treat influenza virus infections by reducing viral sialidase activity requires close monitoring for resistant variants. However, cultured cells do...
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Yoshihiro Kawaoka | P05278US
Technology
Nanoparticles That Target Dendritic Cells
Dendritic cells play an important role in the process of initiating immune response. They are present in small quantities in tissues, such as skin and lung, that are in contact with the external envir...
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Ferencz Denes, Zsuzsanna Fabry, Matyas Sandor | P07026US
Technology
Novel Candidates for an Improved Tuberculosis Vaccine
Approximately one-third of the world’s population is infected with the bacterium Mycobacterium tuberculosis, the causative agent of tuberculosis (TB). Five to 10 percent of non-immunocompromised i...
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Adel Talaat, Bassam Abomoelak, Sarah Ward | P09203US02