Recent advances have started to permit the use of magnetic resonance (MR), instead of the more common X-ray technique, for medical monitoring and control of certain therapeutic procedures, otherwise k...
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Tissue stresses and strains are important measures of biomechanical function. Tissue stiffness aids in determining whether tissue is healthy, damaged, healing or pathological in some other way. Ultras...
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In a computed tomography (CT) system, an X-ray source projects a fan-shaped beam, which passes through the object being imaged and hits an array of radiation detectors. The source and detector array a...
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The HYPR method, as described in WARF reference number P06088US, reconstructs a composite image from acquired data to provide a priori knowledge of the subject being imaged. This composite image then ...
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In a computed tomography (CT) system, an X-ray source projects a fan-shaped beam, which passes through the object being imaged and hits an array of radiation detectors. The source and detector array a...
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Phase contrast magnetic resonance imaging (PC MRI) can be used to improve diagnostic accuracy of vascular, musculoskeletal and cerebrospinal exams. PC MRI functions by receiving a signal emitted by th...
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In imaging technologies, signal-to-noise ratio (SNR) is a quantitative measure of image quality. In medical imaging specifically, as SNR decreases, it becomes increasingly difficult to differentiate b...
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The HYPR method, as described in WARF reference number P06088US, reconstructs a composite image from acquired data to provide a priori knowledge of the subject being imaged. This composite image then ...
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Chemical shift-based multi-echo water-fat separation methods are used increasingly in MRI clinical applications to distinguish between water and fat nuclear magnetic resonance (NMR) signals. Water and...
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MRI systems have played a major part in safely imaging and diagnosing various bodily ailments.  When human tissue is subjected to a uniform magnetic field from a large magnet, it will vibrate at what...
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Elastography is an acoustical imaging method used to estimate the elastic properties of soft tissue by assessing the tissue in different states of compression. Tissue that exhibits less strain under c...
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Ultrasound-based elasticity imaging is used in medicine for non-invasive analysis of tissue movement and displacement. These types of techniques determine how tissue moves in response to pressure, muc...
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Angiographic exams are typically interested in the arterial vasculature and not in fat or other static background tissues. To remove background tissue during contrast-enhanced magnetic resonance angio...
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Ultrasound scanners transmit an ultrasonic signal into a patient and then receive and analyze an echo signal from the patient’s tissue. In conventional gray scale imaging, the most widely used mode,...
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Position emission tomography (PET) plays a vital role in the diagnosis of health and disease. The long-lived isotope iodine-124 (I-124; half-life 4.2 days) has many features that make it an attractive...
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X-ray mammography is currently the most effective method for detecting early-stage breast cancer; however, mammography suffers from relatively high false positive and false negative rates, requires pa...
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Ultrasound-based elasticity imaging uses signals from conventional diagnostic ultrasound systems to show the mechanical properties of tissue (e.g., stiffness or Poisson’s ratio). In quasi-static ela...
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Microwave-based imaging methods, which exploit the contrast in dielectric properties between normal and malignant tissue, offer a promising alternative to ultrasound and X-ray techniques for imaging b...
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Magnetic resonance imaging (MRI) of heart tissue viability and function typically includes a step in which the inversion time (TI) is set so that the signal from normal heart tissue is suppressed in t...
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UW-Madison researchers previously developed a novel imaging technique for detecting breast cancer (see WARF reference number P01386US). This technique makes use of the sharp contrast in dielectric pro...
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Breast cancer is the second most common diagnosed cancer in women.  Currently in the U.S., 2.4 million women have been diagnosed and treated for breast cancer.  The most common method of detecting b...
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Light-based diagnostics are used to create images of human tissue to detect the development of diseases like cancer. The popularity of light-based diagnostics is growing due to their non-intrusive nat...
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Computed tomography (CT) uses special X-ray equipment to obtain image data from different angles of the body and generate a cross-sectional image of body tissues and organs. Because CT is a non-invasi...
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Ultrasonic elastography reveals disease properties of tissue that go undetected with conventional ultrasound. It accomplishes this by imaging the stiffness properties, or strain, of tissues under comp...
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The Feldkamp (FDK) algorithm is widely used for image reconstruction for cone-beam projections, which are utilized in three-dimensional computed tomography (CT). However, because current FDK-type algo...
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