Wisconsin Alumni Research Foundation

Technology

Research Tool for Protein Conformation Analysis

The three-dimensional structure of proteins can be studied in solution using various methods of covalent and noncovalent labeling in which the readout is accomplished by mass spectrometry (MS). These ...
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Michael Sussman, Juda Shohet, Faraz Choudhury, Joshua Blatz, Benjamin Minkoff, Daniel Benjamin | P160180US02

Technology

Tunable, Silicon-Based Fresnel Lenses

A Fresnel lens or ‘zone plate’ is a type of compact lens made of concentric rings that alternate between opaque and transparent materials. The design is lighter and smaller than conventional lense...
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Hongrui Jiang, Yen-Sheng Lu, Hewei Liu | P140128US01

Technology

Streamlined Design for Transferring Analytes

Polymerase chain reaction (PCR) is used to generate copies of a particular DNA sequence. The technique is common and indispensable in many research applications. Unfortunately, methods for isolating/p...
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David Beebe, Ben Casavant, David Guckenberger, Scott Berry | P130361US01

Technology

Multi-Wavelength Mode-Locked Laser

Many laser applications require multiple, simultaneous laser beams, each with a specific wavelength. But using multiple lasers and associated optical components increases the cost and size of the syst...
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Scott Sanders | P07171US

Technology

Circulating Tumor Cell Assay Using Simple Blood Draw

Circulating tumor cells (CTCs) are cells shed from tumor deposits that flow into the bloodstream. They are detected at a frequency of about one CTC per one billion surrounding blood cells. The great h...
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David Beebe, Joshua Lang, Ben Casavant, Scott Berry, Lindsay Strotman | P130171US01

Technology

New Mass Spectrometry Detector Uses Optically Active Membrane

Mass spectrometers are analytical instruments that can precisely measure the mass of molecules to determine their composition and identity. Generally, the molecules are ionized and then accelerated by...
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Robert Blick, Jonathan Rodriguez, Hyunseok Kim, Zlatan Aksamija, Wolfgang Hansen, Christian Heyn | P140174US01

Technology

Microcavity Method for Single Molecule Spectroscopy

Single molecule spectroscopy and microscopy – a popular tool for biological, biophysical and chemical characterization – generally requires the use of fluorescent molecules. Researchers at UW–M...
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Randall Goldsmith, Kevin Heylman | P140153US03

WARF