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14 Results for 'Arrays'
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Technology
Hydrogel Compositions For Use In Promoting Tubulogenesis
William Murphy, Eric Nguyen, Michael Schwartz, Hamisha Ardalani, Matthew Zanotelli, Matthew Parlato, David Belair, William Daly, Ngoc Nhi Le, Stefan Zorn | P140314US02
Technology
Hydrogel Compositions For Use In Cell Expansion And Differentiation
William Murphy, Matthew Parlato, Ngoc Nhi Le, James Molenda | P150263US01
Technology
Controlling the Formation of Stem Cell Colonies with Tailored SAM Array
The substrate on which cells are cultured is key to successful growth and tissue generation. For example, it has been shown that attachment to a substrate by human embryonic stem cells influences whet...
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William Murphy, Angela Xie | P150062US01
Technology
Hydrogel Arrays for Screening Cell-Substrate Interactions, Now in Multiwell Format
While extensive research has been devoted to understanding the influence of medium conditions on cell development, researchers have only recently begun to understand the role of culture surface proper...
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William Murphy, Ngoc Nhi Le | P140305US01
Technology
Hydrogel Arrays for Screening Cell-Substrate Interactions
While extensive research has been devoted to understanding the influence of medium conditions on cell development, researchers have only recently begun to understand the role of culture surface proper...
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William Murphy, Stefan Zorn, Ngoc Nhi Le, Michael Schwartz, Eric Nguyen | P140097US01
Technology
Assembly of Full-Length Genes from DNA Arrays
The ability to chemically synthesize single-stranded oligonucleotides has had a profound impact on research and medicine. Yet existing strategies have their limitations. One critical limitation is the...
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Lloyd Smith, Cheng-Hsien Wu | P120014US02
Technology
Investigating Cell-Surface Interactions via Chemical Array
How and why precursor cells differentiate into tissue-specific cell types involves a complex interplay of signals and remains a rich topic of investigation. Outside of the body, for example, certain s...
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William Murphy, Justin Koepsel | P120126US01
Technology
Image Locking System for DNA Microarray Synthesis
DNA microarrays, or “chips,” are fabricated by high speed robotics on glass or sometimes nylon substrates. During the process of manufacturing DNA microarrays and synthetic DNA strands, an image i...
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Franco Cerrina, Mo-Huang Li, Changhan Kim | P03329US
Technology
Synthesis of Low-Cost, High-Density DNA Microarrays
A DNA microarray is a collection of microscopic DNA spots arranged on a solid surface via covalent attachment to a chemically suitable substrate. DNA microarrays allow hundreds of thousands of DNA seq...
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Franco Cerrina, Omar Negrete | P08067US
Technology
Methods and Devices for Precisely Dispensing Microvolumes of Fluids
Many applications exist for devices that can deposit tiny volumes of fluids, including flexible electronics and biological microarrays. One of these methods uses quill pins (limited to creating 75-mic...
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Max Lagally, Amit Lal, Chung Hoon Lee, Bradley Larson | P01201US
Technology
Plasma-Enhanced Functionalization of Carbon-Containing Substrates
Before DNA or proteins can be attached to a surface during the making of microarrays, the surface must be functionalized, i.e., chemically prepared to carry functional groups capable of...
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Ferencz Denes, Sorin Manolache, Luis Emilio Cruz-Barba, Max Lagally, Bradley Larson | P03334US
Technology
Light-Directed DNA Synthesis Using Inverse Capping for Error Reduction
Because conventional DNA sequencing using electrophoresis is laborious and time consuming, alternative approaches, such as those using microarrays, have been developed. Photolithographic techniques ar...
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Franco Cerrina, Changhan Kim | P06072US
Technology
Plasma-Enhanced Functionalization of Inorganic Oxide Surfaces
Bioactive surfaces created by binding biomolecules to the surface of inorganic substrates are used in many bioassays, biosensors, and other devices. One common approach to functionalizing surfaces so ...
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Ferencz Denes, Sorin Manolache, Jason Helgren, Max Lagally, Bradley Larson | P04163US
Technology
Using UV Light to Functionalize Metal Oxides for Use in Biosensors, Solar Cells and Other Devices
Functionalized substrates have commercial applications ranging from biosensors to energy conversion devices such as solar cells. Biosensors rapidly detect the presence of target biomolecules bas...
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Robert Hamers, Bo Li, Elizabeth Landis, Ryan Franking | P09033US