The present invention from UW-Madison innovators is a CRISPRi system for studying the genetics of Z. mobilis and lac-regulated synthetic Z. mobilis promoters that are used in the CRISPRi system but al...
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UW researchers have identified a genetic mutation in a family of genes that removes a repressor of the shikimate pathway. Their work identified the suppressor of tyra2 (sota) as a target to deregulate...
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UW-Madison researchers have developed a flow reactor for lignin valorization. The flow-based reactor increases monomer production while limiting unwanted side/subsequent reactions. In particular, mate...
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Recent global estimates project that over 125 million tons of dairy products are wasted or discarded due to spoilage each year. Roughly half of this waste occurs before the products even reach the con...
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UW-Madison researchers have developed an engineered Saccharomyces cerevisiae strain capable of efficient fermentation of xylose to ethanol. The engineered yeast they developed builds upon a previously...
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UW Madison researchers have developed an improved method for the electrochemical reductive coupling of lignin derived monomers (e.g., 4-carboxylic acid phenols) in the presence of Ni or Ni/Pd catalysi...
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Plant biomass remains a promising renewable source of important platform chemicals currently derived from petroleum. These include the chemical building blocks used to make polyurethanes (commonly fou...
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Lignocellulosic biomass is a renewable energy source with great potential for generating value-added chemicals. One of the major components of biomass is lignin (15-25 percent). Due to its infamo...
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UW researchers have developed a simple and efficient method of dissolving biomass using concentrated sulfuric acid and cysteine. The standard method of Klason lignin determination involves dissolving ...
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Recombinant cells and methods for producing methyl ketones, such as medium-chain methyl ketones. The recombinant cells include recombinant acyl-ACP thioesterase genes, recombinant β-ketoacyl-CoA ...
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The invention is directed to BAHD acyltransferase enzymes, nucleic acids encoding BAHD acyltransferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of BAH...
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Worldwide renewable energy sources are in high demand due to climate change combined with rapid depletion of fossil fuel reserves. Bioethanol remains the most attractive choice as an alternative to co...
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The present invention provides isolated gene sequences useful in increasing lignocellulosic toxin tolerance in yeast. Such engineered yeast are useful in methods of biofuel production, particularly et...
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The invention relates to isolated nucleic acids encoding a feruloyl-CoA:monolignol transferase and feruloyl-CoA:monolignol transferase enzymes. The isolated nucleic acids and/or the enzymes enable inc...
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Disclosed is a method for preparing liquid fuel and chemical intermediates from biomass-derived oxygenated hydrocarbons. The method includes the steps of reacting in a single reactor an aqueous soluti...
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A low-temperature catalytic process for converting biomass (preferably glycerol recovered from the fabrication of bio-diesel) to synthesis gas (i.e., H2/CO gas mixture) in an endothermic gasification ...
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Systems and methods for determining genetic variations of an organism for performing a physiological function. The systems include a number of modules that can be integrated into existing metabolic en...
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Unnatural, mutated thioesterases having an amino acid sequence that is at least 80% identical to SEQ. ID. NO: 1 and having substitutions at one or more of amino acid positions I107, R108, L109, S122, ...
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The invention relates to feruloyl-CoA:monolignol transferase enzymes and nucleic acids encoding the feruloyl-CoA:monolignol transferase enzymes. The enzymes and/or the nucleic acids enable incorporati...
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Microorganisms that co-consume glucose with non-glucose carbohydrates, such as xylose, and methods of using same. The microorganisms comprise modifications that reduce or ablate the activity of a phos...
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The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having ...
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A method of processing a solution comprising aromatic compounds. The method includes culturing a first microorganism in the solution for a time sufficient to reduce an amount of an aromatic compound a...
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An ethanologen for producing biofuel from one or more carbohydrates and reducing lactate and acetate production in a biofuel manufacturing process. The ethanologen is made by introducing into the etha...
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The invention is directed to p-coumaroyl-CoA:monolignol transferase enzymes, nucleic acids encoding p-coumaroyl-CoA:monolignol transferase enzymes, and inhibitory nucleic acids adapted to inhibit the ...
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A method to produce levulinic acid (LA) and gamma-valerolactone (GVL) from biomass-derived cellulose or lignocellulose by selective extraction of LA using GVL and optionally converting the LA so isola...
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