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5-Hydroxymethylfurfural (HMF) has been called the “sleeping giant” of building block chemistry and listed among the top 10 biomass-based platform chemicals by the U.S Department of Energy. Reduc...
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Kyoung-Shin Choi, John Roylance | P170001US01

Technology

‘Green’ Tylenol: Synthesizing Acetaminophen from Renewable Biomass

Paracetamol (acetaminophen) is an analgesic and fever-reducing medicine. It is an active ingredient in many widely sold over-the-counter medicines such as Tylenol and Panadol. As a prescription pharma...
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John Ralph, Steven Karlen, Justin Mobley | P170066US02

Technology

Recyclable Catalyst for Lower Cost Production of Fermentable Sugars and High Value Chemicals from Biomass

Lignocellulose is plant biomass that is the most abundantly available raw material on Earth for producing end products such as biofuels and certain high value chemicals. Processes currently exist to s...
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Malek Alkasrawi, Joynal Abedin | T170034US02

Technology

Fatty Acid-Producing Microbes for Generating Medium- and Long-Chain Hydrocarbons

New, renewable sources of transportation fuel are needed to meet continuing demand. While the main focus has been on biomass-derived gasoline alternatives such as ethanol and other short-chain alcohol...
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Brian Pfleger, Rebecca Lennen | P09329US02

Technology

Microbes Produce High Yields of Fatty Alcohols from Glucose

Fatty alcohols are used in detergents, emulsifiers, lubricants and personal care items. More than 1.3 million tons of fatty alcohols are used worldwide each year, representing a $3 billion market. C...
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Brian Pfleger, J. Tyler Youngquist | P140076US02

Technology

High Yield Method to Produce HMF from Fructose

The platform molecule 5-hydroxymethylfurfural (HMF), produced from the dehydration of C6 sugars (hexoses), is considered to be one of the top value-added chemicals. The efficient production of HMF fro...
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James Dumesic, Ali Hussain Motagamwala | P180329US01

Technology

Recombinant High-Lipid Microbe for Bioproduct & Biofuel Production

Lipids derived from microorganisms, including bacteria, yeast and microalgae, offer a promising source of renewable fuels and chemicals. Oleaginous microbes – defined as those accumulating more than...
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Timothy Donohue, Kimberly Lemmer, Weiping Zhang, Daniel Noguera | P170068US02

Technology

Enzymatic Depolymerization of Lignin

Lignin is a renewable resource that accounts for up to 30 percent of the dry weight of vascular plant cell walls. It is comprised of aromatic compounds that may be valuable commodities for the biofuel...
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Timothy Donohue, Daniel Gall, Wayne Kontur, Hoon Kim, John Ralph, Daniel Noguera, Brian Fox, Craig Bingman | P170274US02