Wisconsin Alumni Research Foundation

Technology

VACO6

A UW-Madison researcher has established a cell line, called VACO6, from a discarded tissue specimen of a surgically resected primary human colon cancer. The detailed characteristics of the clinical do...
Learn More
James Willson | P230180US01

Technology

PROBIOTIC STRAIN COLLECTION TO STUDY PROPHAGES

UW-Madison researchers have developed a number of variants of lytic strain L. reuteri ∆Φ1attB1∆Φ2∆attB2 (WARF case P170020). They are: L. reuteri∆Φ1, in which prophage #1 is dele...
Learn More
Jan Peter Van Pijkeren, Jeehwan Oh | P230139US01

Technology

Immortalized Vocal Fold Fibroblasts

Normal vibration of vocal folds (aka vocal cords) depends on the tissue's composition and viscoelasticity. When that composition is altered by scarring or damage, the vibratory functionality of the vo...
Learn More
Susan Thibeault, Xia Chen | P190232US01

Technology

SufFeSient Cells

The commercially available E. coli strain BL21 λDE3 is commonly used for inducibly overexpressing recombinant proteins. Many derivatives of BL21 cells have been developed and commercialized, wi...
Learn More
Patricia Kiley, Erin Mettert | P190138US01

Technology

Vq Myeloma Cell Lines

UW Madison researchers' present invention is a set of two, new transgenic mouse multiple myeloma (MM) cell lines. Transgenic mice were developed expressing mutations in RAS pathway genes found in ...
Learn More
Jing Zhang | P210035US01

Technology

Human Basal Cell Carcinoma Cell Line UW-BCC1

Basal cell carcinoma (BCC) is the most common type of skin cancer, with around 3 million cases diagnosed each year. BCC involves the basal cells, which are in the deepest layer of the epidermis, the o...
Learn More
Vladimir Spiegelman, Felicite Noubissi Kamdem | P140339US01

Technology

CHO Cell Line Expressing HERG-1 Potassium Channels

HERG-1 (human ether-a-go-go-related gene) potassium channels mediate repolarization of cardiac action potentials. Loss of function mutations in hERG-1 can result in long QT syndrome, an inherited diso...
Learn More
Gail Robertson, Barry Ganetzky, Jeffrey Warmke, Matthew Trudeau, Samuel Breit, Terence Campbell, Bruce Walker, Stella Valenzuela | P00082US

Technology

Induced Pluripotent Stem Cell Lines For Fragile X Research

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and is closely linked with autism. The genetic basis of FXS is an expansion of CGG repeats in the 5'-untranslated ...
Learn More
Anita Bhattacharyya Consigny, Su-Chun Zhang, Leonard Abbeduto | P160138US02

Technology

Plasmids And Cell Lines Expressing The DMPK 3'UTR

The UW Madison researchers' invention is a set of plasmid constructs and cell lines developed to investigate the effects of RNA toxicity in myotonic dystrophy. The inventor created two constructs link...
Learn More
Mani Mahadevan, Jeffrey Amack | P210221US01

WARF