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32 Results for 'Protein interactions & function'
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Technology
Microwave Dielectric Spectroscopy Method and Device
Proteins change conformation in solution for a variety of reasons, including events such as ligand binding. Most researchers use simple and readily available optical means to measure protein conformat...
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Daniel van der Weide, Kimberly Taylor | P02102US
Technology
Microfluidics Platform and Method That Mimic the Cellular Environment
Most biochemical interactions are studied in solutions containing dilute concentrations of molecules. However, the complexity of the cellular environment makes it difficult to compare the results of s...
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David Beebe, Jaisree Moorthy, Richard Burgess | P04153US
Technology
Multidimensional Spectrometer
Over the last eight years, academic researchers have been developing a new set of spectroscopic techniques that are multidimensional versions of visible and infrared spectroscopies, such as two-dimens...
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Martin Zanni, Niels Damrauer | P07420US
Technology
Methods for Determining Protein Binding Specificity Using Peptide Libraries
Silent information regulator (SIRT) genes encode sirtuins, a highly conserved class of protein deacetylases that have been implicated in physiological processes and diseases states ranging from aging ...
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John Denu, Adam Garske | P06108US
Technology
Defined Surfaces of Self-Assembled Monolayers and Stem Cells
Human embryonic stem (hES) cells are capable of self-renewal, as long as they remain undifferentiated. Culture conditions, including the medium and substrate the cells are grown in, play an important ...
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Laura Kiessling, James Thomson, Ratmir Derda, Brendan Orner | P05364US
Technology
New Tools for Solubilizing, Isolating and Characterizing Membrane Proteins
Membrane proteins perform many crucial functions in vivo. Physical characterization of these proteins, including the determination of three-dimensional crystal structures, could improve fundamen...
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Samuel Gellman, Pil Seok Chae, Philip Laible, Marc Wander | P07482US
Technology
Methods and Reagents for Appending Functional Groups to Proteins
Molecules that contain two functional groups of distinct reactivity can be used to link two biomolecules or to immobilize a biomolecule on a surface, such as a protein microarray. These bifunctional m...
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Ronald Raines, Jeet Kalia | P04016US