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3 Results for 'Small molecules'
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Technology
GENTLE AND DIRECT COPPER-BASED PROTEIN AZIDYLATION FOR BIOCONJUGATION
UW-Madison researchers have developed an improved and simpler method for rapidly attaching azide (N3) groups to proteins in solution. Whereas the reaction described in P220072 required an oxidative re...
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Michael Sussman, Benjamin Minkoff, Jamison Wolfer, Yun Hu, Jennifer Schomaker | P240219US02
Technology
Biomimetic, Reactive Oxygen Species-Detonable Nanoclusters For Antirestenotic Therapy
UW-Madison researchers along with collaborators engineered a multimodal nanocluster drug delivery particle for treating restenosis. The researchers formed the nanocluster by self-assembly of H40-polyl...
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Shaoqin Gong, Yi Zhao, Kenneth Kent, Lianwang Guo, Bowen Wang, Takuro Shirasu | P210367US02
Technology
HYDROGEL COMPOSITIONS COMPRISING GASDERMIN D AND AN ESCRT INHIBITOR AND METHODS OF USE THEREOF
UW-Madison researchers have developed a novel approach for enhancing pyroptosis, which could prove beneficial in treating cancer. The inventors combine intracellular delivery of gasdermin with a small...
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Quanyin Hu, Zhaoting Li | P220290US02