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8 Results for 'Musculoskeletal'
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Technology
Use Of Neuropeptides For Ligament, Cartilage, And Bone Healing
Disclosed are a method and a corresponding pharmaceutical composition for treating damaged cartilage and subchondral bone. Neurogenic compounds in general and neuropeptides in particular have been fou...
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Ray Vanderby, Kelley Grorud | P05193US
Technology
Botulinum Neurotoxin A Subtype 6 And Pharmacological Methods Of Use
The invention is related to preparation of botulinum toxin A6 and methods of use.
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Eric Johnson, Molly Moritz, Sabine Pellett, Marite Bradshaw, William Tepp | P180058US02
Technology
Methods For The Treatment Of X-Linked Hypophosphatemia And Related Disorders
X-linked hypophosphatemia (XLH) is a genetic type of rickets/osteomalacia marked by progressively severe skeletal abnormalities and growth retardation. It is a renal phosphate wasting disorder, which ...
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Marc Drezner, Baozhi Yuan | P100323US02
Technology
Novel Subtype of Botulinum Toxin for Prolonged Effectiveness
Clostridium botulinum produces botulinum neurotoxin (BoNT), which can cause debilitating disease but also is used to treat disorders like chronic headache, spastic muscles and strabismus.
Several di...
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Eric Johnson, Mark Jacobson, Guangyun Lin, William Tepp, Raymond Stevens, Jerome Dupuy, Paul Stenmark | P09050US02
Technology
Hormone Analogs for Treating Hypoparathyroidism
The proper functioning of cells depends on information traveling from the extracellular environment to the cytoplasm. Most signals must be conveyed via proteins that span the cellular membrane. Many o...
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Samuel Gellman, Ross Cheloha, Thomas Gardella | P130312US03
Technology
Vitamin D Analogs “WT-51” and “WT-52” Boost Bone and Skin Health
Vitamin D (1,25-dihydroxyvitamin D3) is a highly potent regulator of calcium homeostasis and plays an established role in cellular differentiation. An important class of vitamin D analogs, the 19-nor-...
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Hector DeLuca, Lori Plum, Rafal Barycki, Margaret Clagett-Dame | P130007US02
Technology
Method to Diagnose and Treat Degenerative Joint Disease
Joint disease results in huge economic costs and can significantly reduce the quality-of-life of people who suffer from it. Pain, inflammation, and instability of the joint are common. Treatment is ge...
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Peter Muir, Ray Vanderby, Paolo Provenzano | P03092US
Technology
Tat-Utrophin as a Protein Therapy for Muscular Dystrophies
No effective therapy currently exists for the most common and severe form of muscular dystrophy disease, Duchenne Muscular Dystrophy (DMD). This disease, which is characterized by the weakening of vol...
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James Ervasti, Kevin Sonnemann | P06414US