An osseointegrated neural interface (ONI) is provided for control of a prosthetic. The ONI includes an elongated, hollow rod having a first end receivable in an intramedullary cavity of a bone, a seco...
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A device and method are provided for modulating brain inflammation. The device includes a light source positionable at a location adjacent a portion of brain for modulating the inflammation thereof Th...
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The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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A transducer supported by the eardrum provides a piezoelectric material exchanging energy with the eardrum through a nanoscale membrane, the latter serving to boost the coupling between the piezoelect...
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Systems and methods to detect sleep stages of a subject analyze physiological parameters of the subject in combination with a subject's reactions to stimuli of increasing intensity and/or stimuli havi...
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Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
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The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related...
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The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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A system is configured to provide sensory stimuli to a subject at a first intensity level, determine the effectiveness of the provided sensory stimuli, and incrementally increase the intensity level o...
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The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge witho...
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The present disclosure pertains to a system configured to detect transitions in sleep state of a subject during a sleep session; provide sensory stimulation to the subject with a timing based on the d...
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The present disclosure pertains to a system configured to adjust an intensity of sensory stimulation delivered to a subject during a sleep session based on sleep spindles in the subject during the sle...
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A system is configured to provide sensory stimuli to a subject at a first intensity level, determine the effectiveness of the provided sensory stimuli, and incrementally increase the intensity level o...
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The present disclosure pertains to a system for enhancing knowledge consolidation in a subject during sleep. New declarative memories may be better consolidated by presenting sensory stimuli during sl...
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The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on slow wave activity in the subject during the sleep session. Slo...
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Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Each year approximately 780,000 Americans experience a new or recurrent stroke.  Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of ...
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During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
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Research confirms that following injury the adult brain is capable of remarkable adjustments to take on changes in motor and sensory experience. For the four million Americans living with the effects ...
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Hydrocephalus is a disorder in which a subject’s body produces cerebrospinal fluid (CSF) at a rate faster than the venous system is able to absorb the fluid. The increase in intracranial pressur...
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Studying how neurons and other cells work may require stimulating individual or small clusters of cells. The cells conventionally are stimulated through the use of fine electrodes inserted into or nea...
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Studying how neurons and other cells work may require stimulating individual or small clusters of cells.  The cells conventionally are stimulated through the use of fine electrodes inserted into ...
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One of the frontiers in biomedical science is the development of brain-computer interface (BCI) systems. A need exists for small-scale neurological interfaces that can potentially transmit information...
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Cerebral aneurysms develop when the wall of a cerebral artery or vein become weakened and the blood vessel begins to balloon. To avoid this type of complication, procedures have been developed to prev...
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