UW researchers have devised a novel technique called histoplasty. Histoplasty is an innovative non-invasive, non-thermal, and non-ionizing focused ultrasound (FUS) technology like high intensity focus...
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UW Madison researchers have developed a system and method for counteracting the off-target effects of neuromodulation therapy by adding a second specially synchronized “nullification” waveform. �...
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UW-Madison researchers have developed a method to provide improved stimulation over time to compensate for electrode location variability. The method identifies effective stimulation points using a s...
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UW researchers and collaborators have developed a method that quantifies and monitors the degree of local functional alteration in the brain after structural damage from stroke, tumor growth, or traum...
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Measurement of intracranial pressure (ICP) can be used to determine risk levels for head trauma, hydrocephalus, and craniosynostosis in patients. In one clinical application, elevated ICP is a highly ...
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This case is joint and was filed by Columbia University. A UW researcher, in collaboration with researchers from Columbia University and Medical University of South Carolina, have created a system an...
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UW researchers along with collaborators have developed a method for determining the presence of consciousness in a patient suffering from disorders of consciousness such as coma patients, vegetative s...
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Waste removal from the central nervous system (CNS) is essential for maintaining brain homeostasis. Disruption of waste clearance can lead to protein accumulation. The aggregation of pathogenic protei...
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Waste removal from the central nervous system (CNS) is essential for maintaining brain homeostasis. Disruption of waste clearance can lead to protein accumulation. The aggregation of pathogenic protei...
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An osseointegrated neural interface (ONI) is provided for control of a prosthetic. The ONI includes an elongated, hollow rod having a first end receivable in an intramedullary cavity of a bone, a seco...
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The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on slow wave activity in the subject during the sleep session. Slo...
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Systems and methods to detect sleep stages of a subject analyze physiological parameters of the subject in combination with a subject's reactions to stimuli of increasing intensity and/or stimuli ...
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The present disclosure pertains to a system for enhancing knowledge consolidation in a subject during sleep. New declarative memories may be better consolidated by presenting sensory stimuli during sl...
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A system is configured to provide sensory stimuli to a subject at a first intensity level, determine the effectiveness of the provided sensory stimuli, and incrementally increase the intensity level o...
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A transducer supported by the eardrum provides a piezoelectric material exchanging energy with the eardrum through a nanoscale membrane, the latter serving to boost the coupling between the piezoelect...
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The present disclosure pertains to a system configured to adjust an intensity of sensory stimulation delivered to a subject during a sleep session based on sleep spindles in the subject during the sle...
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The present disclosure pertains to a system configured to detect transitions in sleep state of a subject during a sleep session; provide sensory stimulation to the subject with a timing based on the d...
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The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge w...
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The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related...
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The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
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Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Each year approximately 780,000 Americans experience a new or recurrent stroke.  Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of long...
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During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
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