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Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Bermans Iskandar, Joshua Medow, Christopher Luzzio, John Webster, Mehdi Shokoueinejad Maragheh, Fa Wang, Xuan Zhang | P170214US01

Technology

Improved System for Stroke Therapy and Rehabilitation

Each year approximately 780,000 Americans experience a new or recurrent stroke. Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of ...
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Justin Williams, Vivek Prabhakaran | P09245US02

Technology

Improved Neuron Electrode Array Uses Graphene

During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
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Zhenqiang Ma, Justin Williams, Dong-Wook Park, Amelia Schendel, Solomon Mikael | P140254US01

Technology

Virtual Reality Rehabilitation for Stroke Victims

Research confirms that following injury the adult brain is capable of remarkable adjustments to take on changes in motor and sensory experience. For the four million Americans living with the effects ...
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Andrea Mason, Leigh Ann Mrotek, David Kettner | P120323US01

Technology

Gravity- and Pressure-Controlled Valve System for Controlling Cerebrospinal Fluid in the Ventricular System

Hydrocephalus is a disorder in which a subject’s body produces cerebrospinal fluid (CSF) at a rate faster than the venous system is able to absorb the fluid. The increase in intracranial pressur...
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David Hsu, Bermans Iskandar, Murielle Hsu | P110042US01

Technology

Microtube Scaffold for Sensing and Stimulating Nerve Cell Connections

Studying how neurons and other cells work may require stimulating individual or small clusters of cells. The cells conventionally are stimulated through the use of fine electrodes inserted into or nea...
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Robert Blick, Justin Williams, Minrui Yu, Yu Huang | P100158US01

Technology

Nanoscale and Microscale Wireless Stimulating Probes Precisely Deliver Electrical Current to Cells

Robert Blick, Max Lagally | P07076US

Technology

Implantable Intracranial Neural Interface System

One of the frontiers in biomedical science is the development of brain-computer interface (BCI) systems. A need exists for small-scale neurological interfaces that can potentially transmit information...
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P. Charles Garell, Justin Williams, Daryl Kipke, Jaimie Henderson, Jamille Hetke | P04169US

Technology

Improved Endovascular Aneurysm Occlusion Device

Cerebral aneurysms develop when the wall of a cerebral artery or vein become weakened and the blood vessel begins to balloon. To avoid this type of complication, procedures have been developed to prev...
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Kristyn Masters, Wendy Crone, Roham Moftakhar, Fangmin Xu, Beverly Aagaard-Kienitz | P08088US

Technology

Monitoring Consciousness for Improved Anesthesia Delivery

Anesthetics are a critical part of modern surgical practice. Unfortunately, once in every 1000 to 2000 operations a patient may temporarily regain consciousness or even remain conscious during surgery...
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Giulio Tononi | P09238US02

Technology

Medical Shunt and Valve for Regulating Bodily Fluids, Especially Cerebral Spinal Fluid

No way currently exists to prevent or cure hydrocephalus, which is the abnormal accumulation of cerebral spinal fluid (CSF) in the brain. The most effective treatment involves surgical insertion of a ...
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Christopher Luzzio, Joshua Medow | P03355US