Measurement of intracranial pressure (ICP) can be used to determine risk levels for head trauma, hydrocephalus, and craniosynostosis in patients. In one clinical application, elevated ICP is a highly ...
Learn More

This case is joint and was filed by Columbia University. A UW researcher, in collaboration with researchers from Columbia University and Medical University of South Carolina, have created a system an...
Learn More

UW researchers and collaborators have developed a method that quantifies and monitors the degree of local functional alteration in the brain after structural damage from stroke, tumor growth, or traum...
Learn More

UW researchers along with collaborators have developed a method for determining the presence of consciousness in a patient suffering from disorders of consciousness such as coma patients, vegetative s...
Learn More

Waste removal from the central nervous system (CNS) is essential for maintaining brain homeostasis. Disruption of waste clearance can lead to protein accumulation. The aggregation of pathogenic protei...
Learn More

Waste removal from the central nervous system (CNS) is essential for maintaining brain homeostasis. Disruption of waste clearance can lead to protein accumulation. The aggregation of pathogenic protei...
Learn More

An osseointegrated neural interface (ONI) is provided for control of a prosthetic. The ONI includes an elongated, hollow rod having a first end receivable in an intramedullary cavity of a bone, a seco...
Learn More

The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on slow wave activity in the subject during the sleep session. Slo...
Learn More

Systems and methods to detect sleep stages of a subject analyze physiological parameters of the subject in combination with a subject's reactions to stimuli of increasing intensity and/or stimuli havi...
Learn More

The present disclosure pertains to a system for enhancing knowledge consolidation in a subject during sleep. New declarative memories may be better consolidated by presenting sensory stimuli during sl...
Learn More

A system is configured to provide sensory stimuli to a subject at a first intensity level, determine the effectiveness of the provided sensory stimuli, and incrementally increase the intensity level o...
Learn More

A transducer supported by the eardrum provides a piezoelectric material exchanging energy with the eardrum through a nanoscale membrane, the latter serving to boost the coupling between the piezoelect...
Learn More

The present disclosure pertains to a system configured to adjust an intensity of sensory stimulation delivered to a subject during a sleep session based on sleep spindles in the subject during the sle...
Learn More

The present disclosure pertains to a system configured to detect transitions in sleep state of a subject during a sleep session; provide sensory stimulation to the subject with a timing based on the d...
Learn More

The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge witho...
Learn More

The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related...
Learn More

The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
Learn More

The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
Learn More

Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
Learn More

Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
Learn More

Each year approximately 780,000 Americans experience a new or recurrent stroke.  Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of ...
Learn More

During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
Learn More

Hydrocephalus is a disorder in which a subject’s body produces cerebrospinal fluid (CSF) at a rate faster than the venous system is able to absorb the fluid. The increase in intracranial pressur...
Learn More

Studying how neurons and other cells work may require stimulating individual or small clusters of cells. The cells conventionally are stimulated through the use of fine electrodes inserted into or nea...
Learn More

One of the frontiers in biomedical science is the development of brain-computer interface (BCI) systems. A need exists for small-scale neurological interfaces that can potentially transmit information...
Learn More