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39 Results for 'Neurological devices'
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Technology
LOCALIZING ION-CHANNEL ACTIVATION USING NULLIFYING WAVEFORMS
UW Madison researchers have developed a system and method for counteracting the off-target effects of neuromodulation therapy by adding a second specially synchronized “nullification” waveform. �...
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Kip Ludwig, James Trevathan | P240381US01
Technology
NEURAL STIMULATION DEVICE MONITORING EVOKED SIGNALS
UW-Madison researchers have developed a method to provide improved stimulation over time to compensate for electrode location variability. The method identifies effective stimulation points using a s...
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Kip Ludwig, Rex Chin-Hao Chen, James Trevathan, Brandon Coventry | P230418US01
Technology
Method and Apparatus for Assessing Electrocortical Consequences of Brain Injury
UW researchers and collaborators have developed a method that quantifies and monitors the degree of local functional alteration in the brain after structural damage from stroke, tumor growth, or traum...
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Giulio Tononi, Christof Koch, Marcello Massimini, Simone Sarasso, Mario Rosanova | P220192WO01
Technology
IMPLANTABLE PRESSURE SENSING DEVICE FOR LONGITUDINAL INTRACRANIAL PRESSURE MONITORING
Measurement of intracranial pressure (ICP) can be used to determine risk levels for head trauma, hydrocephalus, and craniosynostosis in patients. In one clinical application, elevated ICP is a highly ...
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Daniel Cho, Jessica Blum, James Trevathan, John Puccinelli, Michael Del Signore, Lucas Cates, Ipek Naz Kadioglu, Caroline Craig, Karina Buttram, Joseph Ho, Adrienne Simpson, Vivian Woo | P230183US01
Technology
CLOSED-LOOP SIMULTANEOUS FUNCTIONAL MAGNETIC RESONANCE IMAGING (fMRI)-ELECTROENCEPHALOGRAM (EEG)-TRANSCRANIAL MAGNETIC STIMULATION (TMS) SYSTEM
This case is joint and was filed by Columbia University.
A UW researcher, in collaboration with researchers from Columbia University and Medical University of South Carolina, have created a system an...
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Robin Goldman, Paul Sajda, Truman Brown, Mark George, Josef Faller, Jayce Doose, James Mclntosh, Joshua Teves, Yida Lin, Golbarg Saber, Aidan Blankenship, Spiro Pantazatos, Xiaoxiao Sun | P220208US02
Technology
Method and Apparatus for Detecting Consciousness
UW researchers along with collaborators have developed a method for determining the presence of consciousness in a patient suffering from disorders of consciousness such as coma patients, vegetative s...
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Giulio Tononi, Christof Koch, Marcello Massimini, Silvia Casarotto, Michele Colombo | P220191WO01
Technology
USE OF NON-INVASIVE SENSORY SYSTEMS TO TITRATE CRANIAL NERVE STIMULATION TO ENHANCE BRAIN CLEARANCE CLOSED-LOOP
Waste removal from the central nervous system (CNS) is essential for maintaining brain homeostasis. Disruption of waste clearance can lead to protein accumulation. The aggregation of pathogenic protei...
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Kip Ludwig, Justin Williams, Nishant Verma | P220059US02
Technology
LAYERED STIMULUS PATTERNING TO SYNERGISTICALLY OPTIMIZE BRAIN CLEARANCE AT MULTIPLE POINTS IN CLEARANCE SYSTEM AND REAL-TIME DIAL TO CHANGE DRUG DELIVERY PROFILES
Waste removal from the central nervous system (CNS) is essential for maintaining brain homeostasis. Disruption of waste clearance can lead to protein accumulation. The aggregation of pathogenic protei...
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Kip Ludwig, Justin Williams, Kevin Cheng, Nishant Verma | P220055US02
Technology
Osseointegrated Neural Interface And Method
An osseointegrated neural interface (ONI) is provided for control of a prosthetic. The ONI includes an elongated, hollow rod having a first end receivable in an intramedullary cavity of a bone, a seco...
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Samuel Poore, Justin Williams, Sarah Brodnick, Thomas Richner, Sahil Kapur | P150260US01
Technology
System And Method For Sleep Session Management Based On Slow Wave Sleep Activity In A Subject
The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on slow wave activity in the subject during the sleep session. Slo...
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Giulio Tononi, Brady Riedner, Michele Bellesi, Gary Garcia Molina, Sander Pastoor, Stefan Pfundtner | P130098US02
Technology
Sensory Stimuli To Increase Accuracy Of Sleep Staging
Systems and methods to detect sleep stages of a subject analyze physiological parameters of the subject in combination with a subject's reactions to stimuli of increasing intensity and/or stimuli ...
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Giulio Tononi, Brady Riedner, Michele Bellesi, Gary Garcia Molina, Stefan Pfundtner, Sander Pastoor | P130092US02
Technology
System And Method For Enhanced Knowledge Consolidation By Sleep Slow Wave Induction And Sensory Context Re-Creation
The present disclosure pertains to a system for enhancing knowledge consolidation in a subject during sleep. New declarative memories may be better consolidated by presenting sensory stimuli during sl...
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Giulio Tononi, Michele Bellesi, Gary Garcia Molina, Joanne Westerink | P130096US02
Technology
Adjustment Of Sensory Stimulation Intensity To Enhance Sleep Slow Wave Activity
A system is configured to provide sensory stimuli to a subject at a first intensity level, determine the effectiveness of the provided sensory stimuli, and incrementally increase the intensity level o...
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Giulio Tononi, Michele Bellesi, Brady Riedner, Gary Garcia Molina | P130129US02
Technology
Eardrum Transducer With Nanoscale Membrane
A transducer supported by the eardrum provides a piezoelectric material exchanging energy with the eardrum through a nanoscale membrane, the latter serving to boost the coupling between the piezoelect...
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Max Lagally, Abhishek Bhat, Frank Flack, Shelley Scott, Robert Blick | P180314US01
Technology
System And Method For Adjusting The Intensity Of Sensory Stimulation During Sleep Based On Sleep Spindles
The present disclosure pertains to a system configured to adjust an intensity of sensory stimulation delivered to a subject during a sleep session based on sleep spindles in the subject during the sle...
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Giulio Tononi, Michele Bellesi, Brady Riedner, Gary Garcia Molina, Stefan Pfundtner | P140363US02
Technology
System And Method For Determining Timing Of Sensory Stimulation Delivered To A Subject During A Sleep Session
The present disclosure pertains to a system configured to detect transitions in sleep state of a subject during a sleep session; provide sensory stimulation to the subject with a timing based on the d...
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Giulio Tononi, Michele Bellesi, Brady Riedner, Juan Benzo, Gary Garcia Molina | P140136US02
Technology
Self-Powered, Auto-Responsive Implanted Vagal Nerve Stimulator For Weight Control
The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge w...
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Xudong Wang, Weibo Cai, Guang Yao, Lei Kang | P180263US01
Technology
System And Method For Delivering Sensory Stimulation During Sleep Based On Demographic Information
The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related...
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Giulio Tononi, Brady Riedner, Gary Garcia Molina, Tsevetomira Tsoneva | P180370US02
Technology
Neuromodulation To Modulate Glymphatic Clearance
The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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Justin Williams, Kip Ludwig, Erika Ross | P170016US02
Technology
System And Method For Adjusting The Volume Of Auditory Stimulation During Sleep Based On Sleep Depth Latencies
The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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Giulio Tononi, Brady Riedner, Gary Garcia Molina, Michele Bellesi | P160412US02
Technology
Penetration Of Cerebral Spinal Fluid Into The Brain Parenchyma Using Temporally Patterned Neuromodulation
Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
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Justin Williams, Kip Ludwig, Angela Williams, Samuel Poore | P190197US02
Technology
‘Smart’ Cerebrospinal Fluid Shunt
Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Bermans Iskandar, Joshua Medow, Christopher Luzzio, John Webster, Mehdi Shokoueinejad Maragheh, Fa Wang, Xuan Zhang | P170214US01
Technology
Improved System for Stroke Therapy and Rehabilitation
Each year approximately 780,000 Americans experience a new or recurrent stroke. Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of long...
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Justin Williams, Vivek Prabhakaran | P09245US02
Technology
Improved Neuron Electrode Array Uses Graphene
During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
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Zhenqiang Ma, Justin Williams, Dong-Wook Park, Amelia Schendel, Solomon Mikael | P140254US01
Technology
Gravity- and Pressure-Controlled Valve System for Controlling Cerebrospinal Fluid in the Ventricular System
Hydrocephalus is a disorder in which a subject’s body produces cerebrospinal fluid (CSF) at a rate faster than the venous system is able to absorb the fluid. The increase in intracranial pressure (I...
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David Hsu, Bermans Iskandar, Murielle Hsu | P110042US01