An osseointegrated neural interface (ONI) is provided for control of a prosthetic. The ONI includes an elongated, hollow rod having a first end receivable in an intramedullary cavity of a bone, a seco...
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A device and method are provided for modulating brain inflammation. The device includes a light source positionable at a location adjacent a portion of brain for modulating the inflammation thereof Th...
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The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on slow wave activity in the subject during the sleep session. Slo...
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Systems and methods to detect sleep stages of a subject analyze physiological parameters of the subject in combination with a subject's reactions to stimuli of increasing intensity and/or stimuli havi...
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The present disclosure pertains to a system for enhancing knowledge consolidation in a subject during sleep. New declarative memories may be better consolidated by presenting sensory stimuli during sl...
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A system is configured to provide sensory stimuli to a subject at a first intensity level, determine the effectiveness of the provided sensory stimuli, and incrementally increase the intensity level o...
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A transducer supported by the eardrum provides a piezoelectric material exchanging energy with the eardrum through a nanoscale membrane, the latter serving to boost the coupling between the piezoelect...
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The present disclosure pertains to a system configured to adjust an intensity of sensory stimulation delivered to a subject during a sleep session based on sleep spindles in the subject during the sle...
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The present disclosure pertains to a system configured to detect transitions in sleep state of a subject during a sleep session; provide sensory stimulation to the subject with a timing based on the d...
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The invention provides an implantable vagal nerve stimulator having a “passive” generating power source that harvests the stomach's movements to transform kinetic energy to electrical charge witho...
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The present disclosure pertains to delivering sensory stimulation to a user during a sleep session. In some embodiments, sensors are configured to generate output signals conveying information related...
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The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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The present disclosure pertains to a system configured to adjust a volume of auditory stimulation delivered to a subject during sleep. The system is configured to determine a deepening time indicative...
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Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time c...
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Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Each year approximately 780,000 Americans experience a new or recurrent stroke.  Approximately 85 percent of these patients survive and require rehabilitation, making stroke the leading cause of ...
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During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
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Hydrocephalus is a disorder in which a subject’s body produces cerebrospinal fluid (CSF) at a rate faster than the venous system is able to absorb the fluid. The increase in intracranial pressur...
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Studying how neurons and other cells work may require stimulating individual or small clusters of cells. The cells conventionally are stimulated through the use of fine electrodes inserted into or nea...
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One of the frontiers in biomedical science is the development of brain-computer interface (BCI) systems. A need exists for small-scale neurological interfaces that can potentially transmit information...
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Studying how neurons and other cells work may require stimulating individual or small clusters of cells.  The cells conventionally are stimulated through the use of fine electrodes inserted into ...
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Cerebral aneurysms develop when the wall of a cerebral artery or vein become weakened and the blood vessel begins to balloon. To avoid this type of complication, procedures have been developed to prev...
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Anesthetics are a critical part of modern surgical practice. Unfortunately, once in every 1000 to 2000 operations a patient may temporarily regain consciousness or even remain conscious during surgery...
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No way currently exists to prevent or cure hydrocephalus, which is the abnormal accumulation of cerebral spinal fluid (CSF) in the brain. The most effective treatment involves surgical insertion of a ...
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As many as one in 20 people in the United States are estimated to have some form of cerebral aneurysm. The majority of cerebral aneurysms are treated from inside the blood vessel, which is referred to...
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