Wisconsin Alumni Research Foundation

Technology

NEURAL STIMULATION DEVICE MONITORING EVOKED SIGNALS

UW-Madison researchers have developed a method to provide improved stimulation over time to compensate for electrode location variability. The method identifies effective stimulation points using a s...
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Kip Ludwig, Rex Chin-Hao Chen, James Trevathan, Brandon Coventry | P230418US01

Technology

IMPLANTABLE PRESSURE SENSING DEVICE FOR LONGITUDINAL INTRACRANIAL PRESSURE MONITORING

Measurement of intracranial pressure (ICP) can be used to determine risk levels for head trauma, hydrocephalus, and craniosynostosis in patients. In one clinical application, elevated ICP is a highly ...
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Daniel Cho, Jessica Blum, James Trevathan, John Puccinelli, Michael Del Signore, Lucas Cates, Ipek Naz Kadioglu, Caroline Craig, Karina Buttram, Joseph Ho, Adrienne Simpson, Vivian Woo | P230183US01

Technology

CLOSED-LOOP SIMULTANEOUS FUNCTIONAL MAGNETIC RESONANCE IMAGING (fMRI)-ELECTROENCEPHALOGRAM (EEG)-TRANSCRANIAL MAGNETIC STIMULATION (TMS) SYSTEM

This case is joint and was filed by Columbia University. A UW researcher, in collaboration with researchers from Columbia University and Medical University of South Carolina, have created a system an...
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Robin Goldman, Paul Sajda, Truman Brown, Mark George, Josef Faller, Jayce Doose, James Mclntosh, Joshua Teves, Yida Lin, Golbarg Saber, Aidan Blankenship, Spiro Pantazatos, Xiaoxiao Sun | P220208US02

Technology

Method and Apparatus for Detecting Consciousness

UW researchers along with collaborators have developed a method for determining the presence of consciousness in a patient suffering from disorders of consciousness such as coma patients, vegetative s...
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Giulio Tononi, Christof Koch, Marcello Massimini, Silvia Casarotto, Michele Colombo | P220191WO01

Technology

Osseointegrated Neural Interface And Method

An osseointegrated neural interface (ONI) is provided for control of a prosthetic. The ONI includes an elongated, hollow rod having a first end receivable in an intramedullary cavity of a bone, a seco...
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Samuel Poore, Justin Williams, Sarah Brodnick, Thomas Richner, Sahil Kapur | P150260US01

Technology

Sensory Stimuli To Increase Accuracy Of Sleep Staging

Systems and methods to detect sleep stages of a subject analyze physiological parameters of the subject in combination with a subject's reactions to stimuli of increasing intensity and/or stimuli ...
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Giulio Tononi, Brady Riedner, Michele Bellesi, Gary Garcia Molina, Stefan Pfundtner, Sander Pastoor | P130092US02

Technology

Eardrum Transducer With Nanoscale Membrane

A transducer supported by the eardrum provides a piezoelectric material exchanging energy with the eardrum through a nanoscale membrane, the latter serving to boost the coupling between the piezoelect...
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Max Lagally, Abhishek Bhat, Frank Flack, Shelley Scott, Robert Blick | P180314US01

Technology

Neuromodulation To Modulate Glymphatic Clearance

The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopat...
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Justin Williams, Kip Ludwig, Erika Ross | P170016US02

Technology

‘Smart’ Cerebrospinal Fluid Shunt

Hydrocephalus is a life-threatening condition caused by abnormal accumulation of cerebrospinal fluid within the ventricles of the brain. Typically it is treated through the surgical placement of a shu...
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Bermans Iskandar, Joshua Medow, Christopher Luzzio, John Webster, Mehdi Shokoueinejad Maragheh, Fa Wang, Xuan Zhang | P170214US01

Technology

Improved Neuron Electrode Array Uses Graphene

During electrocorticography (ECoG), electrodes are placed directly on the exposed surface of the brain or spinal cord to record electrical signals. The practice is used to conduct neuroscience researc...
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Zhenqiang Ma, Justin Williams, Dong-Wook Park, Amelia Schendel, Solomon Mikael | P140254US01

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