Wisconsin Alumni Research Foundation

Technology

In Vitro Model Of Spinal Muscular Atrophy

A population of iPS cells derived from somatic cells from a spinal muscular atrophy patient is disclosed. In one embodiment of the invention, the cells have been cultured to produce neural cells. In a...
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Clive Svendsen, Allison Ebert | P09194US02

Technology

Inorganic Coatings For The Enhancement Of Chemical Transfection

Disclosed are methods for cell transfection and regulating cellular behavior. More particularly, the present disclosure relates to methods of non-viral cell transfection and regulating cellular behavi...
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William Murphy, Andrew Khalil, Xiaohua Yu, Krishanu Saha, Jared Carlson-Stevermer, Benjamin Steyer | P150078US01

Technology

Hydrogel Compositions For Use In Promoting Tubulogenesis

Hydrogel Compositions and methods of using hydrogel compositions are disclosed. Advantageously, the hydrogel compositions offer the ability to rapidly screen substrate components for influencing cell ...
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William Murphy, Eric Nguyen, Michael Schwartz, Hamisha Ardalani, Matthew Zanotelli, Matthew Parlato, David Belair, William Daly, Ngoc Nhi Le, Stefan Zorn | P140314US02

Technology

Hydrogel Arrays for Screening Cell-Substrate Interactions

While extensive research has been devoted to understanding the influence of medium conditions on cell development, researchers have only recently begun to understand the role of culture surface proper...
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William Murphy, Stefan Zorn, Ngoc Nhi Le, Michael Schwartz, Eric Nguyen | P140097US01

Technology

Multilayer Tissue Regeneration System

Under physiological conditions, bone tissue regeneration involves a complex interplay of multiple biologically active molecules and stem cells. The molecules are often presented sequentially in cascad...
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William Murphy | P05256US

WARF