Wisconsin Alumni Research Foundation

Technology

Broadly protective influenza B virus vaccines

UW-Madison researchers have developed a series of mutant influenza B viruses that incorporate mutations in the HA1 protein that cause the virus to react with sera generated via exposure to the opposit...
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Yoshihiro Kawaoka, Gabriele Neumann | P220144US02

Technology

RECOMBINANT MULTIVALENT INFLUENZA VIRUSES

The present invention relates to a novel bivalent coronavirus/influenza virus vaccine (called CoroFlu). The vaccine comprises a coronavirus antigen (a secreted version of the spike (S) protein of SARS...
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Yoshihiro Kawaoka, Gabriele Neumann | P200263US02

Technology

NEUTRALIZING VACCINES AGAINST HUMAN CORONAVIRUS

The present invention provides both QuilA-loaded chitosan (QAC)-encapsulated DNA vaccine compositions and viral vaccine compositions that encode a SARs-CoV-2 spike (S) protein, a SARs-CoV-2 nucleocaps...
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Adel Talaat, Shaswath Chandrasekar | P210042US02

Technology

COVID-19 Vaccine

Provided herein are antigenic peptides comprising the SARS-CoV-2 spike protein receptor binding domain (CRBD) polypeptide or portions thereof, linked to a non-catalytic, non­toxic tetanus toxin varia...
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Joseph Barbieri, Eric Johnson, Sabine Pellett, William Tepp, Amanda Przedpelski | P200268US03

Technology

RSV Virus-Like Particles And Methods Of Use Thereof

The present disclosure relates to vims-like particles and vaccine compositions for inducing immunity and preventing respiratory syncytial vims (RSV) infection. Specifically, the disclosure provides vi...
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Elizabeth Wright, Larry Anderson, Binh Ha | P200021US02

Technology

Influenza Virus Replication For Vaccine Development

The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isola...
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Yoshihiro Kawaoka, Gabriele Neumann, Jihui Ping | P150360US02

WARF