Wisconsin Alumni Research Foundation

Radiation Therapy
Radiation Therapy
Sharpening Filter for Orthovoltage Radiation
WARF: P170240US01

Inventors: Jessica Fagerstrom, Edward Bender, Wesley Culberson, Michael Lawless, Benjamin R. M. Palmer, Larry DeWerd

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a collimator specifically designed for use with orthovoltage radiation to provide a sharper dose profile.

This innovation may enable orthovoltage radiation treatment of neurological tumors at significantly less expense than existing stereotactic radiosurgery systems.

Stereotactic radiosurgery (SRS) is a specialized form of radiation therapy that uses a precise, highly localized photon beam to treat small tumors especially in the brain. Reducing beam energy from the standard megavoltage range to the lower orthovoltage energy range would offer many advantages, including space, cost and dosimetric benefits.
The Invention
UW–Madison researchers have developed a compact filter that increases the sharpness of orthovoltage pencil beams and may be tailored to different beam sizes and focus depths.

The technology features a specially designed collimator and filter disk having concentric circular attenuation regions to produce the necessary sharpening effect. The flat design of the filter disk supports easy installation and replacement, and the concentric circular attenuation regions are amenable to computerized optimization of the region sizes and spacing.
  • For use in medical orthovoltage radiation systems as well as small animal research irradiators to sharpen beam dose delivery
  • Treatment of neurological tumors
  • Installed system likely featuring several different filters, which could be interchanged for a specific radiation treatment plan
Key Benefits
  • Improves operation, versatility and manufacturability
  • Filter can be easily installed and removed from collimator block.
  • Provides clinician a wide range of filtration options
Additional Information
For More Information About the Inventors
For current licensing status, please contact Jeanine Burmania at [javascript protected email address] or 608-960-9846