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216 Results for 'Analytical Instrumentation, Methods & Materials'
PAGE 1 OF 9
Technology
UW-Madison researchers have developed a novel mass spectrometry (MS)-based method for simultaneous qualitative and quantitative protein citrullination analysis from biological and clinical samples. Th...
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Lingjun Li, Yatao Shi, Zihui Li | P190302US02
Technology
COHERENT LIGHT SOURCE BASED ON COLLECTIVE SPONTANEOUS EMISSION
Coherent light sources, in which the photons have highly matched frequencies and phases, are commonly produced by lasers. In a laser, the atoms of a laser medium are stimulated to excite the electrons...
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Deniz Yavuz, Mark Saffman, David Gold, Thad Walker | P220098US02
Technology
Matrices and systems for preservation of biomolecules in vacuum
UW-Madison and Morgridge Institute researchers have identified developed an improved method for depositing samples on electron microscopy (EM) grids. The technology leverages a modified mass spectrome...
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Joshua Coon, Michael Westphall, Kenneth Lee, Austin Salome, Timothy Grant, Jean Lodge | P220041WO01
Technology
CELL-BASED DNA SENSORS AND METHODS OF USING SAME
UW-Madison researchers have developed cell-based DNA sensors to achieve easy, accurate, and cost-effective detection of pathogens. Using synthetic biology, the inventors engineered the naturally compe...
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Ophelia Venturelli, Yu-Yu Cheng, Zhengyi Chen | P210411US02
Technology
METHODS AND SYSTEMS FOR COHERENT MULTIDIMENSIONAL SPECTROSCOPY
A UW-Madison researcher has developed an improved method and associated system for coherent multidimensional spectroscopy (CMDS). CMDS is based on the formation of Schrӧdinger cat states by exciting ...
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John Wright | P200249US02
Technology
A NOVEL STRATEGY ENABLED BY A PHOTO-CLEAVABLE SURFACTANT FOR EXTRACELLULAR VESICLE PROTEOMICS
Building off of their prior discovery (Photo-Cleavable Surfactants P180335US02), UW-Madison researchers disclose an improved method for exosome proteomics. The method leverages the researchers’ ...
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Ying Ge, Song Jin, Kyle Brown, Kevin Buck | P220113US02
Technology
Testing the Strength of Soft Materials
Soft materials are everywhere. In many applications, valuable information about the strength of these materials enables more precise control in everything from cutting and processing soft foods to des...
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Melih Eriten, Corinne Henak | P220230US01
Technology
LIQUID CRYSTAL-INFUSED SLIPPERY ANTI-FOULING SURFACES
Building off their earlier work with LC-infused multilayer films, the inventors developed a method for directly infusing LCs into porous PTFE membranes. The resulting materials have desirable ch...
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David Lynn, Harshit Agarwal | P210229US02
Technology
DEVICE AND METHOD FOR CONTROLLING AND CONFIGURING THE SPACIAL AND TEMPORTAL EVOLUTION OF A GRADIENT IN A MICROFLUIDIC ENVIRONMENT
UW-Madison researchers have developed a well-plate for cell culture that allows the user to finely define the location and temporal profile of multiple gradients including oxygen, nutrients, chemoattr...
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David Beebe, Jose Ayuso, Maria Virumbrales-Munoz, Cristina Sanchez de Diego | P220125US01
Technology
RAPID ESTIMATION OF A SOIL-WATER RETENTION CURVE USING VISIBLE-NEAR INFRARED SPECTROSCOPY
UW-Madison researchers have developed improved methods and systems for characterizing soil using visible-near-infrared spectroscopy (vis-NIRS) data. Combining their spectrographic data with additional...
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Jingyi Huang, Zampela Pittaki-Chrysodonta, Alfred Hartemink | P210177US02
Technology
ELECTROMECHANICAL FORCE SENSOR BASED ON EXTREMA DEGENERACY POINT WITH NONLINEAR RESPONSE
UW-Madison researchers and collaborators from Wesleyan University have shown, using an exceptional point (EP)-based PT-symmetric electromechanical accelerometer, that increases in technical noise can ...
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Ramathasan Thevamaran, Jizhe Cai, Tsampikos Kottos, Fred Ellis, Rodion Kononchuk | P220050US01
Technology
ALKALI METAL OPTICAL CLOCK
UW researchers have invented a Cesium Lattice Optical Clock (CLOC) for high performance and simple operation in a compact form factor. The novel design uses a “forbidden” optical transitio...
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Mark Saffman, Shimon Kolkowitz, Arjav Sharma | P220217US01
Technology
RETRACTABLE ION GUIDE, GRID HOLDER, AND TECHNOLOGY FOR REMOVAL OF CRYOGENIC SAMPLE FROM VACUUM
UW-Madison researchers have developed an improved sample handling system for the preparation of samples to be analyzed using cryo-electron microscopy (cryo-EM). The system includes a retractable grid ...
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Joshua Coon, Michael Westphall | P200355US02
Technology
FREEZING AND JACKETING GAS-PHASE BIOMOLECULES WITH AMORPHOUS ICE FOR ELECTRON MICROSCOPY
UW-Madison researchers have developed an improved technique for cryogenically fixing biological samples in amorphous ice for analysis by cryo-electron microscopy (cryo-EM). Analyte particles are...
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Joshua Coon, Michael Westphall | P200354WO01
Technology
SYSTEMS AND METHODS FOR DETERMINING MECHANICAL PROPERTIES IN SUBSURFACE FORMATIONS
A UW-Madison researcher has developed a method for predicting subsurface mechanical properties using distributed strain measurements obtained from applied perturbations. The method relies on model cha...
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Jesse Hampton | P190275WO01
Technology
UW-Madison researchers, working in collaboration with researchers from Cornell, developed metal-oxide based liquid crystal (LC) sensors for monitoring catalytic reactions. The inventors used a previou...
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Emmanouil Mavrikakis, Jake Gold, Trenton Wolter, Nicholas Abbott, Nanqi Bao, Huaizhe Yu, Ayushi Tripathi | P220044US01
Technology
BIOLOGICAL SENSING AND COMMUNICATION USING OPTOGENETICS AND ELECTRONICS
UW–Madison researchers have combined the innate sensing capabilities of biological compounds with the power of electronics to create a hybrid “bio-electronic” network. This enables new biosensor...
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Bhuvana Krishnaswamy, Megan McClean | P200351US02
Technology
SUPER-RESOLUTION OPTICAL MICROSCOPE
UW Madison researchers have devised a simplified super-resolution microscope with resolving features smaller than the diffraction limits of the optical system. The new super-resolution microscope expl...
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Shimon Kolkowitz, Aedan Gardill, Matthew Cambria | P210362US01
Technology
KITS AND METHODS FOR SUPER-RESOLUTION MICROSCOPY
UW Madison Researchers have improved upon conventional expanded microscopy. They have developed novel 4-fold and a 12-fold mExM (modified expansion microscopy) methodologies, which stably and reproduc...
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Aussie Suzuki, Mark Burkard, Roshan Norman, Emma Recchia | P200189US02
Technology
Device And Method Incorporating A Slideable Lid For Extracting A Targeted Fraction From A Sample
A device and a method for isolating a target from a biological sample are provided. The target is bound to solid phase substrate to form target bound solid phase substrate. The device includes a lower...
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David Beebe, David Guckenberger, Ben Casavant, Scott Berry | P120359US01
Technology
Device And Method To Facilitate The Prepackaging, Handling And Use Of Small Volumes Of Fluids
A device and method are provided to facilitate the handling of a volume or fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for rece...
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David Beebe, Jay Warrick, David Guckenberger | P160301US01
Technology
Method And Device For Disaggregation Via Heterogeneous Particles
A method and a device are provided for facilitating the disaggregation of a plurality of solid phase substrate as the plurality of solid phase substrate are transferred from a first location to a seco...
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David Beebe, David Guckenberger, Hannah Pezzi | P160351US01
Technology
Capacitive Touch Sensor
A capacitive touch sensor is provided, The capacitive touch sensor includes a plate having an upper surface and lying in a plate plane. A generally planar, first electrode is spaced from the plate alo...
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Hongrui Jiang, Jayer Fernandes | P160417US01
Technology
High Performance, High Electron Mobility Transistors With Graphene Hole Extraction Contacts
Radiation detectors based on high electron mobility transistors (HEMTs) are provided. Methods for detecting ultraviolet radiation using the HEMTs are also provided. The transistors are constructed fro...
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Zhenqiang Ma, Tzu-Hsuan Chang | P170305US01
Technology
High Mass Accuracy Filtering For Improved Spectral Matching Of High-Resolution Gas Chromatography-Mass Spectrometry Data Against Unit-Resolution Reference Databases
The invention provides methods, systems and algorithms for identifying high-resolution mass spectra. In some embodiments, an analyte is ionized and analyzed using high-resolution mass spectrometry (MS...
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Joshua Coon, Nicholas Kwiecien, Derek Bailey, Michael Westphall | P140184US02