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227 Results for 'Analytical Instrumentation, Methods & Materials'
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Technology
COMPOSITIONS AND METHODS FOR PREPARATION OF A CRYOGENIC ELECTRON MICROSCOPY SAMPLE
A UW-Madison researcher proposes a new strategy that uses small, stress-response proteins to preserve fragile samples during cryo-EM SPA sample preparation. The figure below illustrates the general sa...
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Ci Ji Lim | P230306WO01
Technology
CRYOGENIC SOFT LANDING IMPROVES STRUCTURAL PRESERVATION OF PROTEIN COMPLEXES
UW-Madison and Morgridge researchers have designed and constructed a modified Orbitrap mass spectrometer that contains a lander attachment capable of directing an ion beam to a TEM grid cooled to liqu...
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Joshua Coon, Michael Westphall, Timothy Grant, Keaton Mertz, Colin Hemme, Austin Salome, Scott Quarmby | P240025WO01
Technology
SPECTROMETER WITH SELF-REFERENCED CALIBRATION
A UW-Madison researcher has developed of a compact sensor for measuring the absorption spectra of typical liquids in real time. The solution allows for ATR spectroscopy by providing a baseline measur...
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Scott Sanders | P230013US01
Technology
MICROFLUIDIC DEVICE FOR PROFILING BIOCHEMICAL SAMPLES
UW-Madison Researchers have developed a microfluidic device for profiling cell types, evaluating multiple functional read-outs in an efficient, user-friendly high-throughput manner. The device allows ...
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Jose Ayuso, Rithvik Turaga, Catherine Reed McBain, Seth Zima | P240110US01
Technology
SOIL MOISTURE SENSOR
UW-Madison researchers have developed a battery-less tag that can harvest energy from radio signals above ground and send an active response, which is used to estimate the soil moisture. There are two...
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Bhuvana Krishnaswamy, Yoganand Biradavolu | P240275US01
Technology
HIGH THROUGHPUT INFUSION PEPTIDE MAPPING
UW-Madison researchers have developed a high throughput peptide mapping platform by combining a plate-based sample preparation method with direct injection MS analysis. Protein samples are cleaned, re...
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Joshua Coon, Alexander Hebert | P230059WO01
Technology
High-Speed DNA Sequencing Enabled by a High Sensitivity Nanopore
UW-Madison researchers and others have developed a high-speed sequencing method using a novel nanopore technology. As nucleotides pass through the nanopore, changes in the emitted light frequency enab...
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Robert Blick, Paul Gwozdz, Abhishek Bhat, Wolfgang Hansen, Christian Heyn | P150166US01
Technology
Mass Defect-Based Multiplex Dimethyl Pyrimidinyl Ornithine (DiPyrO) Tags for High-Throughput Quantitative Proteomics and Peptidomics
UW-Madison researchers have developed a novel type of mass defect-based chemical tag for use in quantitative mass spectrometry analyses of proteins, peptides, glycans and metabolites. Mass defect-base...
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Lingjun Li, Dustin Frost, Amanda Buchberger Jones | P150350US02
Technology
Ion Source with Low Turn-On Delay, Jitter
UW-Madison researchers have developed a plasma ion source that exhibits a short delay between voltage application and ion beam initiation with low variance in the observed delay (i.e., jitter). Typica...
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Andrew Seltzman | P170357US01
Technology
High Efficiency Room Temperature Infrared Sensor
UW-Madison researchers have developed a room-temperature infrared sensor with high detection efficiency over a wide IR spectral band. Room-temperature operation makes this technology easier to use tha...
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Hongrui Jiang, Seyyed Mohammad Moghimi | P180031US01
Technology
MODULE TO INTEGRATE SINGLE CELL AUTOFLUORESCENCE LIFETIMES WITH SINGLE-CELL TRANSCRIPTION (SCRNA-SEQ)
UW-Madison and Morgridge Institute for Research researchers have created the first high throughput instrument to integrate single cell autofluorescence lifetimes with single-cell transcription (scRNA-...
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Melissa Skala, Kayvan Samimi, Darcie Moore | P240227US01
Technology
FABRICATION AND USE OF NANOCOILS ON NITROGEN-VACANCY DIAMOND SUBSTRATES FOR MAGNETIC FIELD DETECTION AND MANIPULATION
UW-Madison researchers have created a spiral inductor for on chip electromagnetic signal conversion. The spiral inductors include an electrically conductive spiral coil and a nitrogen vacancy (NV) dia...
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Aviad Hai, Alireza Ousati Ashtiani, Ilhan Bok, Yash Gokhale | P240082US01
Technology
UNDER-OIL EXTRACTION USING EXCLUSIVE LIQUID REPELLENCY FOR CELL ISOLATION
UW-Madison researchers have extended their previously developed "Exclusive Liquid Repellency" (ELR) multi-phase liquid system, by integrating it with a new magnetic isolation platform to per...
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David Beebe, Terry Juang, Sheena Kerr | P240134US01
Technology
METHOD FOR TUNING AN ELECTROCHEMICAL DOUBLE LAYER TO GENERATE SOUND REPRESENTATIVE OF PROPERTIES OF THE DOUBLE LAYER
UW-Madison researchers have developed a new way to monitor the behavior of electrochemical double layers (EDL) by bringing them into spontaneous oscillation. The inventors used a modified multivibrato...
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Marcel Schreier, Christine Lucky, Megan Kelly | P230204US02
Technology
SYSTEM AND METHOD FOR FLEXIBLE MULTI-VARIABLE SENSOR
UW-Madison researchers, in conjunction with an industry partner, have developed a printed serpentine trace that can act as both a temperature sensor and a strain/flow sensor. It is integrated on a sin...
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Joseph Andrews, Muhammadeziz Tursunniyaz, Brian Cardwell | P220185US02
Technology
METHODS FOR FABRICATING OPTICAL METASURFACES
Optical metasurfaces enable unprecedented control over electromagnetic wave manipulation. By leveraging powerful resonance mechanisms supported by subwavelength structures arranged in two-dimensional ...
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Filiz Yesilkoy, Yuber Samir Sanchez Rosas, Wihan Adi | P240127US01
Technology
WIRELESS PASSIVE MECHANICAL VIBRATION MONITOR SYSTEM
Real-time vibration sensing is important in a variety of applications in industry, health care, and environmental monitoring. For example, vibration monitoring can assist in the prediction of natural ...
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Chu Ma, Dajun Zhang, Bhuvana Krishnaswamy, Muhammad Shahid | P240131US01
Technology
SYSTEMS AND METHODS FOR LABEL-FREE SENSING OF NEUTROPHIL ACTIVATION
UW-Madison researchers have developed a unique inherent autofluorescent image-based classifiers neutrophil activation. The specific autofluorescence signatures are used to identify neutrophil activati...
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Melissa Skala, Rupsa Datta, Alexandra Walsh | P220289US02
Technology
DEVICES AND METHODS FOR LABEL-FREE SENSING OF LYMPHOCYTE ACTIVATION AND IDENTITY
UW-Madison researchers have developed a unique inherent fluorescent image-based classifiers for B cell and NK cell activation. The specific autofluorescence signatures are used to identify B cell acti...
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Melissa Skala, Rebecca Schmitz, Alexandra Walsh | P220288US02
Technology
NON-INVASIVE MULTIPARAMETER SENSOR
In conjunction with their industrial partner, UW-Madison researchers have created a passive capacitive sensor that uses thin-film electrodes placed in an interdigitated pattern to sense a variety of k...
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Joseph Andrews, Brian Cardwell, Muhammadeziz Tursunniyaz | P230430US01
Technology
METHOD AND APPARATUS FOR EVALUATING SOFT MATERIAL PROPERTIES USING NONLINEAR VIBRATIONS
Characterizing the mechanical properties of multiphasic materials can be important in many applications. In the food industry, for instance, such characterization can help evaluate dehydration and aid...
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Melih Eriten, Karthik Yerrapragada, Haocheng Yang | P240104US01
Technology
LONG DISTANCE WIRELESS RADIO TAG WITH RF ENERGY HARVESTING
The range of passive RFID tags is constrained by three factors. The first is that the reflected energy to the reader rapidly decreases with distance between the reader and the RFID tag both with respe...
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Bhuvana Krishnaswamy, Yaman Sangar, Kai Pederson | P230128US02
Technology
APPARATUS AND METHOD FOR DIRECT NITRATE SENSING IN SOIL
Nitrate is a nutrient that helps plants grow, but too much of it can be harmful. Nitrate monitoring can be used to reduce the amount of fertilizer needed, which is better for the environment and can ...
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Joseph Andrews, Jingyi Huang, Aatresha Biswas | P230143US01
Technology
Fluorescent Indicator of Lithium Ions
UW-Madison researchers have developed a novel profluorophore that binds to lithium ions with high specificity, inducing a fluorescent signal. The fluorescent indicator can be seamlessly integrated int...
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Randall Goldsmith | P150162US02
Technology
MICROFLUIDIC DEVICE AND METHOD FOR GENERATING A SKIN CONSTRUCT
Research into new therapies for skin diseases is challenging for a number of reasons. As is known, skin cells are exposed to both atmospheric air and liquids within the body. However, conventional cel...
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Jose Ayuso, Catherine Reed McBain, Seth Zima, Rithvik Turaga, Vijayasaradhi Setaluri | P230351US01