The use of mass defect signatures to impart milliDalton mass differences between isotopically labeled peptides at the MS1-level allows multiplex quantification without the increased mass spectral comp...
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An ion source device for producing an ion beam may include a housing having an opening, a first electrode, and a second electrode. A portion of the first electrode and the second electrode may be loca...
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The functional effect of having additional color-sensing cone types in the human eye is implemented by an encoding of some spectral information differently for the left and right eyes. This different ...
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An optical field sensor is used to make phase measurements over an area of light reflected from an object outside a field of view of the light field sensor. These phase measurements are applied to a m...
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The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from...
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Lidar is an acronym for Light Detection And Ranging. The technology may be used to measure distance by illuminating a target with a laser beam and performing analysis on the reflected laser beam light...
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An infrared (IR) detection sensor for detecting IR radiation. The IR detection sensor including a plurality of nanowires positioned adjacent to each other so as to define a layer. The layer has an out...
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A method of sample preparation for streamlined multi-step assays is provided. The method includes the step of providing a microfluidic device including a reservoir defined by a surface configured to r...
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A method and device of creating a lumen model in a microwell plate defining a well is provided. A rod is inserted through the well of the microwell plate and the well is filled with a polymerizable ma...
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A microfluidic device and method of assaying for immune cell exhaustion therewith are provided. The microfluidic device includes a moveable rod positioned across a chamber of a microfluidic device adj...
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A method (100) can be provided to determine the throughput speed v of at least one pore (1), comprising: • feeding (110), using a driving force F, a filiform calibration element (2) through the pore...
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Methods for pump-probe spectroscopy are provided. In an embodiment, such a method comprises directing pump light having a frequency ωpump at a location in a sample to excite a transition between two ...
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An apparatus for measurement of surface relief provides a phase sensitive camera and processing to reconstruct a wavefront profile matching the surface when illuminated with a known light source there...
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An improved non-line-of-sight camera provides for real-time evaluation of a relay wall with respect to illuminated points and sensing areas for higher accuracy and practical field use. Gated sensing a...
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A hybrid electrostatic actuator for use in conjunction with microfluidic devices, microlenses, optical irises and flat panel displays is provided. The hybrid electrostatic actuator includes a substrat...
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The present invention provides a set of novel isobaric chemical tags, also referred herein as SUGAR (Isobaric Multiplex Reagents for Carbonyl Containing Compound). These labeling tags are compact and ...
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A new cancer treatment being studied at a few major centers including UW Health is CAR T (Chimeric Antigen Receptor T cell) therapy. CAR T therapy uses a patient's own cells and 'reengineers' them to ...
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The importance of T cells in immunotherapy is driving the development of technologies to better characterize T cells and improve therapeutic efficacy. One specific objective is assessing antigen-induc...
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Optical phase tuning is highly desired in many precision and imaging tools used by industry, in medicine and in biological research. Various optical phase shifters (OPS) and methods exist, each with c...
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Quantum cascade lasers (QCLs) are made of layered semiconductor materials. The structures’ cores are composed of tens of stages, each of which consists of three regions: an electron injector, an...
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Bacterial contamination is a major risk in biologics manufacturing and the presence of endotoxin, an outer membrane component of Gram-negative bacteria, is vigorously tested for in protein and DNA/RNA...
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Mass spectrometry is a broadly applicable analysis tool for detecting and characterizing molecules and other chemical species, including complex mixtures of biomolecules such as peptides, proteins or ...
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Extraction and isolation of nucleic acids from biological samples is an essential prerequisite for further amplification, detection and quantification of specific genetic sequences. The first step in ...
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Volatile organic compounds (VOCs) are found in common household and industrial products. These toxic and/or carcinogenic compounds such as toluene, benzene and styrene are difficult to detect and pers...
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The three-dimensional structure of proteins can be studied in solution using various methods of covalent and noncovalent labeling in which the readout is accomplished by mass spectrometry (MS). These ...
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