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325 Results for 'Research Tools'
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Technology
Simple Biological Method and Device for Detecting a Toxin or Other Chemical
Most schemes for detecting toxins or other chemicals are based on complex electronic, photonic and/or electrochemical methods, or on more elegant biomolecular methods, such as ELISA (Enzyme-Linked Imm...
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David Beebe, Dongshin Kim | P06373US
Technology
Smart Leaf Technology - Floating Semiconductor Membranes for Wireless Sensing
Sensors currently used for detecting the presence of a given analyte, such as a toxin, in solution or in air require direct contact with a power supply. Distributed sensing systems or “sensor networ...
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Robert Blick, Robert Nowak | P05404US
Technology
Methods of Manufacturing and Using Beta-Peptide Lyotropic Liquid Crystals
Liquid crystals have been widely explored for applications such as display and sensing technologies. Lyotropic liquid crystals, which become more ordered as they become more concentrated within a solv...
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Samuel Gellman, Nicholas Abbott, William Pomerantz | P06005US
Technology
Using Stromal Collagen to Help Diagnose and Characterize Breast Cancer
Biomedical imaging allows physicians to detect the onset of disease, injury and other disorders at an early stage, and to monitor their progression.
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Patricia Keely, Paolo Provenzano, John White, Kevin Eliceiri | P06061US
Technology
Methods and Reagents for Appending Functional Groups to Proteins
Molecules that contain two functional groups of distinct reactivity can be used to link two biomolecules or to immobilize a biomolecule on a surface, such as a protein microarray. These bifunctional m...
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Ronald Raines, Jeet Kalia | P04016US
Technology
Methods and Materials for Assaying Non-SCD1 Isoforms
Stearoyl-CoA desaturase (SCD) is the rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids. Inhibitors of SCD may be useful therapeutics for diseases such as obesity and diabetes.
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James Ntambi, Makoto Miyazaki | P05362US
Technology
Bacterial Genomic Libraries from Alaskan Soils (AK 19, 20 and 21)
Cultured microorganisms produce an extraordinary array of structurally diverse and valuable organic compounds; however, microbes that can be cultured using standard techniques represent only a small f...
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Jo Handelsman, Lynn Williamson, Jitsupang Rodbumrer | P06160US
Technology
Bacterial Genomic Libraries from Alaskan Soils (AK 22 and 23)
Cultured microorganisms produce an extraordinary array of structurally diverse and valuable organic compounds; however, microbes that can be cultured using standard techniques represent only a small f...
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Jo Handelsman, Lynn Williamson | P07199US
Technology
Laboratory Mouse Procedural Techniques Training DVD and Manual
When using live vertebrate animals, principal investigators for any activity supported by a Public Health Service (PHS) agency, such as the FDA, NIH or CDC, must comply with the PHS policy on Humane C...
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John Bogdanske, Margaret Riley, Scott Hubbard-Van Stelle, Beth Schiffman | P07411US
Technology
Enhancing the Production of Foreign Proteins in Yeast by Overexpressing Endogenous Genes
Although the yeast Saccharomyces cerevisiae is often used to express foreign proteins for industrial or therapeutic uses, production of these heterologous proteins is far from optimal. Current methods...
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Eric Shusta, Alane Wentz | P07168US
Technology
Collection of Genomic Fragments That Affect Quorum Sensing
Quorum sensing is a process used by some bacteria to coordinate behavior based on local population density. To communicate, bacteria release signaling molecules into the environment. When a certain nu...
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Jo Handelsman, Heather Allen, Lynn Williamson | P06060US
Technology
Full-Length cDNA Libraries from Dioxin- and Vehicle-Treated Mice
Dioxin is a highly toxic environmental pollutant that acts primarily through the aryl hydrocarbon receptor. Exposure to dioxin has adverse effects on the immune, nervous, endocrine and reproductive sy...
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Christopher Bradfield, Kalyan Pande | P06227US
Technology
Mouse Model of Glaucoma
Glaucoma is a group of diseases that can result in vision loss and blindness. According to the World Health Organization, glaucoma is the second leading cause of blindness worldwide. Glaucoma causes a...
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Robert Nickells | P06465US
Technology
Polyclonal Antibody That Recognizes the Sulfonylurea Receptor 1 Isoform
Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
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Jonathan Makielski, Nian-Qing Shi, Bin Ye | P07041US
Technology
Polyclonal Antibody That Recognizes the Sulfonylurea Receptor 2 Isoform
Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
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Jonathan Makielski, Nian-Qing Shi, Bin Ye | P08021US
Technology
Polyclonal Antibody That Recognizes Both Isoforms of the Sulfonylurea Receptor
Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
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Jonathan Makielski, Nian-Qing Shi, Bin Ye | P08022US
Technology
Polyclonal Antibody That Recognizes the 2A Variant of the Sulfonylurea Receptor
Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
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Jonathan Makielski, Nian-Qing Shi, Bin Ye | P08023US
Technology
Polyclonal Antibody That Recognizes the 2B Variant of the Sulfonylurea Receptor
Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
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Jonathan Makielski, Nian-Qing Shi, Bin Ye | P08024US
Technology
Transgenic Zebrafish for Studying Neutrophil Chemotaxis and Inflammation
Neutrophils, the most common type of white blood cells, undergo a process called chemotaxis that helps them travel toward sites of inflammation. Because inflammation plays a central role in the pathog...
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Jonathan Mathias, Anna Huttenlocher | P06337US
Technology
Mouse Monoclonal Antibodies to Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)
Epstein-Barr virus (EBV) is one of the most common human viruses and also is associated with some rare cancers. EBV nuclear antigen 1 (EBNA-1) is involved in replication and transcriptional regulation...
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Richard Burgess, Sarah Duellman, Nancy Thompson, Katherine Mary Foley | P07324US
Technology
Monoclonal Antibodies Against Human Rhinovirus Type 16, a Model Virus for the Common Cold
Human rhinoviruses are the most frequent cause of the common cold. Human rhinovirus 16 (HRV16) is a widely used model virus for studying the common cold, virus-induced asthma and rhinovirus transmissi...
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Wai-Ming Lee | P08176US
Technology
Mouse Monoclonal Antibody Against the Sigma70 Subunit of E. coli RNA Polymerase
RNA polymerase is the enzyme responsible for DNA transcription, the process of making an RNA copy of a DNA gene sequence. Transcription begins at DNA sequences called promoters. In bacteria, a sigma f...
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Richard Burgess, Nancy Thompson | P07502US
Technology
Mouse Monoclonal Antibody Against the Alpha Subunit of E. coli RNA Polymerase
RNA polymerase is the enzyme responsible for DNA transcription, the process of making an RNA copy of a DNA gene sequence. The core RNA polymerase enzyme in E. coli consists of two alpha subunits, a be...
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Richard Burgess, Nancy Thompson | P07503US
Technology
Polyclonal Antibodies to CARM1
The enzyme CARM1 (coactivator associated arginine methyltransferase1) plays an important role in controlling development and cell growth. This nuclear hormone receptor co-activator is involved in the ...
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Wei Xu | P08238US
Technology
Model for Stearoyl-CoA Desaturase Activity
Stearoyl-CoA desaturase (SCD) is the rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids. Inhibitors of SCD may be useful as therapeutic agents for the treatment of diseases such a...
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James Ntambi, Makoto Miyazaki | P06455US