When using live vertebrate animals, principal investigators for any activity supported by a Public Health Service (PHS) agency, such as the FDA, NIH or CDC, must comply with the PHS policy on Humane C...
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Although the yeast Saccharomyces cerevisiae is often used to express foreign proteins for industrial or therapeutic uses, production of these heterologous proteins is far from optimal. Current methods...
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Quorum sensing is a process used by some bacteria to coordinate behavior based on local population density. To communicate, bacteria release signaling molecules into the environment. When a certain nu...
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Dioxin is a highly toxic environmental pollutant that acts primarily through the aryl hydrocarbon receptor. Exposure to dioxin has adverse effects on the immune, nervous, endocrine and reproductive sy...
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Glaucoma is a group of diseases that can result in vision loss and blindness. According to the World Health Organization, glaucoma is the second leading cause of blindness worldwide. Glaucoma causes...
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Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
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Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
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Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Neutrophils, the most common type of white blood cells, undergo a process called chemotaxis that helps them travel toward sites of inflammation. Because inflammation plays a central role in the pathog...
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Epstein-Barr virus (EBV) is one of the most common human viruses and also is associated with some rare cancers. EBV nuclear antigen 1 (EBNA-1) is involved in replication and transcriptional regulation...
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Human rhinoviruses are the most frequent cause of the common cold. Human rhinovirus 16 (HRV16) is a widely used model virus for studying the common cold, virus-induced asthma and rhinovirus transmissi...
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RNA polymerase is the enzyme responsible for DNA transcription, the process of making an RNA copy of a DNA gene sequence. Transcription begins at DNA sequences called promoters. In bacteria, a sigma f...
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RNA polymerase is the enzyme responsible for DNA transcription, the process of making an RNA copy of a DNA gene sequence. The core RNA polymerase enzyme in E. coli consists of two alpha subunits, a be...
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The enzyme CARM1 (coactivator associated arginine methyltransferase1) plays an important role in controlling development and cell growth. This nuclear hormone receptor co-activator is involved in the ...
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Stearoyl-CoA desaturase (SCD) is the rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids. Inhibitors of SCD may be useful as therapeutic agents for the treatment of diseases such a...
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