Sensors currently used for detecting the presence of a given analyte, such as a toxin, in solution or in air require direct contact with a power supply. Distributed sensing systems or “sensor ne...
Learn More

Liquid crystals have been widely explored for applications such as display and sensing technologies. Lyotropic liquid crystals, which become more ordered as they become more concentrated within a solv...
Learn More

Biomedical imaging allows physicians to detect the onset of disease, injury and other disorders at an early stage, and to monitor their progression.
Learn More

Molecules that contain two functional groups of distinct reactivity can be used to link two biomolecules or to immobilize a biomolecule on a surface, such as a protein microarray. These bifunctional m...
Learn More

Stearoyl-CoA desaturase (SCD) is the rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids. Inhibitors of SCD may be useful therapeutics for diseases such as obesity and diabetes.
Learn More

Cultured microorganisms produce an extraordinary array of structurally diverse and valuable organic compounds; however, microbes that can be cultured using standard techniques represent only a small f...
Learn More

Cultured microorganisms produce an extraordinary array of structurally diverse and valuable organic compounds; however, microbes that can be cultured using standard techniques represent only a small f...
Learn More

Purification and separation are the most expensive steps in manufacturing modern biologicals, which include soluble proteins, nucleic acids, viruses and small molecules.
Learn More

When using live vertebrate animals, principal investigators for any activity supported by a Public Health Service (PHS) agency, such as the FDA, NIH or CDC, must comply with the PHS policy on Humane C...
Learn More

Although the yeast Saccharomyces cerevisiae is often used to express foreign proteins for industrial or therapeutic uses, production of these heterologous proteins is far from optimal. Current methods...
Learn More

Quorum sensing is a process used by some bacteria to coordinate behavior based on local population density. To communicate, bacteria release signaling molecules into the environment. When a certain nu...
Learn More

Dioxin is a highly toxic environmental pollutant that acts primarily through the aryl hydrocarbon receptor. Exposure to dioxin has adverse effects on the immune, nervous, endocrine and reproductive sy...
Learn More

Glaucoma is a group of diseases that can result in vision loss and blindness. According to the World Health Organization, glaucoma is the second leading cause of blindness worldwide. Glaucoma causes...
Learn More

Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Sulfonylurea receptors (SURs) regulate the opening and closing of ATP-sensitive potassium channels (KATP). They play important roles in insulin secretion in the pancreas and myocardial protection in t...
Learn More

Because ethanol can be produced from sugars derived from renewable plant biomass, it offers a promising alternative to non-renewable fossil fuels. Corn is currently the main source of carbon used in e...
Learn More

Neutrophils, the most common type of white blood cells, undergo a process called chemotaxis that helps them travel toward sites of inflammation. Because inflammation plays a central role in the pathog...
Learn More

Epstein-Barr virus (EBV) is one of the most common human viruses and also is associated with some rare cancers. EBV nuclear antigen 1 (EBNA-1) is involved in replication and transcriptional regulation...
Learn More

Human rhinoviruses are the most frequent cause of the common cold. Human rhinovirus 16 (HRV16) is a widely used model virus for studying the common cold, virus-induced asthma and rhinovirus transmissi...
Learn More

RNA polymerase is the enzyme responsible for DNA transcription, the process of making an RNA copy of a DNA gene sequence. Transcription begins at DNA sequences called promoters. In bacteria, a sigma f...
Learn More

RNA polymerase is the enzyme responsible for DNA transcription, the process of making an RNA copy of a DNA gene sequence. The core RNA polymerase enzyme in E. coli consists of two alpha subunits, a be...
Learn More

The enzyme CARM1 (coactivator associated arginine methyltransferase1) plays an important role in controlling development and cell growth. This nuclear hormone receptor co-activator is involved in the ...
Learn More