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7 Results for 'General pluripotent cell technologies'
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Technology
SOMATIC CELL REPROGRAMMING
The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The inventi...
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James Thomson, Junying Yu | P08167US
Technology
PLURIPOTENT STEM CELLS OBTAINED BY NON-VIRAL REPROGRAMMING
Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disc...
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James Thomson, Junying Yu | P09113US02
Technology
Oct4 And Sox2 With Sv40 T Antigen Produce Pluripotent Stem Cells From Primate Somatic Cells
Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disc...
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James Thomson, Junying Yu | P09113US04
Technology
Anti-Inflammatory Macrophages And Uses Thereof
The invention relates to a purified, novel anti-inflammatory population of macrophage and methods of making and using such macrophage.
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Peiman Hematti, Jaehyup Kim | P09357US02
Technology
Gene Editing Tool Uses New Enzyme
Genome editing has proven difficult in cells, especially mammalian cells. One way to improve efficiency is to introduce a double-strand break (DSB) in the desired DNA region. These DSBs stimulate cell...
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James Thomson, Zhonggang Hou, Yan Zhang, Rakhi Rajan, Erik Sontheimer, Alfonso Mondragón | P130315US02
Technology
Spatial Control of Signal Transduction
Development of most tissue types involves a complex interplay of multiple growth factors in well defined locations, leading to controlled differentiation of precursor cells into mature, tissue-specifi...
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William Murphy, Gregory Hudalla | P05255US
Technology
Method and System for Delivering Nucleic Acid into a Target Cell
The normal growth and development of tissue requires a complex interplay of multiple signals from multiple genes in well-defined locations, leading to the controlled differentiation of precursor cells...
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William Murphy, Siyoung Choi | P06064US