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32 Results for 'Other medical devices'
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Technology
ORAL BITE BLOCK FOR ENDOTRACHEAL TUBE
A UW Madison physician and local dentist have designed a specialized bite block device for use with endotracheal tubes. The device protects the front teeth by using the molars on both sides of the ja...
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Joshua Medow, Matthew Roggensack | P230240US01
Technology
DELIVERY OF BIOLOGICS VIA MINERAL CRYSTALS FOR REGENERATIVE MEDICINE APPLICATIONS
UW-Madison researchers have developed a nanocrystals capable of delivering biologic payloads. Exemplary payloads include nucleic acids, proteins, and peptides, all of which have shown promise as vacci...
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William Murphy, Gianluca Fontana, Andrew Khalil, Jae Sung Lee | P170373US02
Technology
BIOMATERIALS COATING FOR ON-DEMAND BACTERIA DELIVERY AND METHOD TO TREAT COLITIS AND IRRITABLE BOWEL SYNDROME
Two UW-Madison researchers have developed a sequential coating strategy to improve the efficacy of probiotics used in the treatment of IBD. The probiotic is first coated with a tannic acid (TA) ...
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Quanyin Hu, Jun Liu | P210279WO01
Technology
COMPOSITE CHITOSAN-TANNIN-ACTIVE AGENT COMPOSITIONS AND METHODS OF MAKING AND USING SAME
The inventors have developed methods for creating tannin-chitosan composite thin-films incorporating active pharmaceutical ingredients, including psilocybin (a psychedelic) and biosimilars (melatonin ...
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Jess Reed, Christian Krueger | P210152US02
Technology
ACTIVE MICRONEEDLE ARRAY FOR BREECHING AND PERFORATING THE STRATUM CORNEUM
An active microneedle array and method are provided for penetrating an outer layer of an epidermis. The active microneedle array includes a base having first and second sides. The first side of the ba...
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David Beebe, Benjamin Moga | P08246US
Technology
Apparatus For Intraoperative Ligament Load Measurements
Axial stress or similar properties in a stressed connective tissue may be assessed during surgery by excitation of the ligament to create a shear wave allowing measurement of the shear wave velocity w...
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Darryl Thelen, Jack Martin, Joshua Roth | P180019US01
Technology
Prosthetic Apparatus And Method Therefor
Various aspects of the present disclosure characterize apparatuses and/or methods as may be implemented with a variety of prosthetic components and applications. As may be consistent with one or more ...
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Peter Adamczyk, Luke Steinbach, Michael Hahn | P170381US01
Technology
Stent Apparatus And Method
A bone stent facilitates bone fixation via interior contact, as may be useful for flexible entry into a sidewall of an elongated bone. As consistent with one or more embodiments, a stent includes prox...
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Matthew Halanski, Taylor Jaraczewski, Lucas Schimmelpfenning, Stephen Kernien, Cody Bindl, Kyle Jamar | P130359US01
Technology
Microorganisms And Methods For Producing Biologics And Introducing Biologics To Sites
Microorganisms comprising a maltose-inducible promoter and methods of use in producing biologics and introducing biologics to sites in a maltose-dependent manner. The microorganisms include a maltose-...
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Jan Peter Van Pijkeren, Jeehwan Oh | P170009US02
Technology
Ergonomically Configrued Muscle Release Office Chair
An office chair that is ergonomically configured to allow for the coordination of stretches to the pectoralis minor muscle, trapezius muscle, and scalene muscles to open up the thoracic outlet, releas...
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Shwetha Simhan, Manasi passi-Simhan | P170299US02
Technology
Dendrimer-Exosome Hybrid Nanoparticles As A Delivery Platform
Described herein are hybrid nanoparticles that are exosomes loaded with one or more nanoparticle dendrimers. Also included are pharmaceutical compositions including the hybrid nanoparticles and method...
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Seungpyo Hong, Sin-jung Park | P170201US02
Technology
In Vivo Gene Therapy Delivery Procedure Device
A “localizable” systemic gene therapy system is provided substantially increasing the transfection efficiency of the gene vectors into targeted tissue cells and substantially reducing the escape o...
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Susan Hagness, Erik Aiken, John Booske, Hans Sollinger, Paul Laeseke, Tausif Alam | P180245US01
Technology
Mineral Coated Microparticles For Co-Delivery Of Anti-Inflammatory Molecules With Nucleic Acids To Improve Gene Delivery Outcomes
Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonuclei...
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William Murphy, Andrew Khalil, Xiaohua Yu | P170170US02
Technology
Mineral Coated Microparticles For Gene Delivery In Chronic Wound Therapy
Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral l...
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William Murphy, Andrew Khalil, Xiaohua Yu | P170173US02
Technology
Mineral Coated Microparticles For Sustained Delivery Of Biologically Active Molecules
Disclosed are formulations for providing an active agent. Formulations include a carrier including an active agent and mineral coated microparticles wherein an active agent is adsorbed to the mineral....
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William Murphy, Anna Clements, Connie Chamberlain, Ray Vanderby | P170072US02
Technology
Electric Bandage For Accelerated Wound Recovery
A wearable medical bandage is provided having an energy harvesting generator that harvests mechanical energy from the user's natural body and muscle motions to produce electrical energy. The electrica...
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Xudong Wang, Yin Long, Weibo Cai, Hao Wei | P180067US01
Technology
Slippery Liquid-Infused Porous Surfaces (SLIPS) with Improved Antifouling Properties, Small Molecule Release
Slippery liquid-infused porous surfaces (SLIPS) are an emerging class of materials with unique antifouling properties and applications ranging from biomedical device coatings and consumer products to ...
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David Lynn, Uttam Manna | P160308US02
Technology
Growth Factor Regulation in Blood Products for Improved Wound Healing
Growth factor regulation is a key function of the extracellular matrix and critical for proper blood vessel growth and maturation during wound healing. In particular, blood vessel sprouting is essenti...
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William Murphy, David Belair, Ngoc Nhi T. Le, Michael Toepke, Nicholas Impellitteri, Connie Chamberlain | P160179US01
Technology
More Stable Collagen Mimetic Peptides for Wound Healing
Collagen is the most abundant protein in vertebrates, providing support to virtually every tissue including skin, bone and blood vessel. It is of critical importance in wound healing.
Given its signi...
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Ronald Raines, Ismet Tanrikulu | P140407US02
Technology
Implantable Cancer Drug Delivery Device Signals the Future of Personalized Medicine
Cancer treatment planning remains an ongoing challenge to oncologists and patients alike, with each cancer being genetically unique and requiring personalized approaches. Greater outcome success will ...
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David Beebe, Mark Burkard, Jay Warrick, David Guckenberger, Lee Wilke | P150255US01
Technology
An Orthopedic Implant Coating for Enhanced Bone Growth
"Orthobiologics" provides an improved method of treating fractures and other bone defects. This therapy employs inductive molecules, such as bone morphogenetic protein-2 or bone morphogeneti...
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William Murphy, Jae Sam Lee, Mark Markel, Ben Graf | P07031US
Technology
Calibrated Drill Sleeve Also Protects Soft Tissue
Drills are commonly used during orthopedic surgery to place screws that allow fixation of fractured bones. One problem that surgeons face while drilling is the overlying soft tissue becoming entangled...
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Kenneth Xu, Austin Crow, Josh Kolz, Sarah Sandock, John Renfrew | P120364US01
Technology
Microfluidic Device for Drug Delivery
Oral ingestion of pharmaceuticals is considered the safest, most convenient and most economical method of administering drugs. However, many pharmaceuticals cannot be delivered orally because they are...
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David Beebe, Michael MacDonald, David Eddington, Glennys Mensing | P04240US
Technology
Click Chemistry-Based Multi-Enhanced Biomaterials Help Heal Wounds
Wound healing is a complex and dynamic process of rebuilding skin and tissue. Chronic or impaired wounds result when tissues fail to progress through the necessary stages of healing. This is a signifi...
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Weiyuan John Kao, Yao Fu | P100330US02
Technology
Biodegradable, Biocompatible Tannin-Chitosan Composites for Therapeutic Applications
Chitosan is a soluble biopolymer derived from chitin, which is a structural element in the shell of marine arthropods. Chitosan is used in water processing and agriculture. It also is used...
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Jess Reed, Christian Krueger, Sergio Madrigal-Carballo | P09128US02