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William Murphy, Gianluca Fontana, Bernard Binder, Glenn Gaudette, Joshua Gershlak, Pamela Weathers, Tanja Dominko, Marsha Rolle, Sarah Hernandez, Carole Cramer, Fabricio Medina-Bolivar | P160290US03

Technology

Ergonomically Configrued Muscle Release Office Chair

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Shwetha Simhan, Manasi passi-Simhan | P170299US02

Technology

Microorganisms And Methods For Producing Biologics And Introducing Biologics To Sites

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Jan Peter Van Pijkeren, Jeehwan Oh | P170009US02

Technology

Slippery Liquid-Infused Porous Surfaces (SLIPS) with Improved Antifouling Properties, Small Molecule Release

Slippery liquid-infused porous surfaces (SLIPS) are an emerging class of materials with unique antifouling properties and applications ranging from biomedical device coatings and consumer products to ...
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David Lynn, Uttam Manna | P160308US02

Technology

Growth Factor Regulation in Blood Products for Improved Wound Healing

Growth factor regulation is a key function of the extracellular matrix and critical for proper blood vessel growth and maturation during wound healing. In particular, blood vessel sprouting is essenti...
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William Murphy, David Belair, Ngoc Nhi Le, Michael Toepke, Nicholas Impellitteri, Connie Chamberlain | P160179US01

Technology

More Stable Collagen Mimetic Peptides for Wound Healing

Collagen is the most abundant protein in vertebrates, providing support to virtually every tissue including skin, bone and blood vessel. It is of critical importance in wound healing. Given its signi...
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Ronald Raines, Ismet Tanrikulu | P140407US02

Technology

Implantable Cancer Drug Delivery Device Signals the Future of Personalized Medicine

Cancer treatment planning remains an ongoing challenge to oncologists and patients alike, with each cancer being genetically unique and requiring personalized approaches. Greater outcome success will ...
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David Beebe, Mark Burkard, Jay Warrick, David Guckenberger, Lee Wilke | P150255US01

Technology

An Orthopedic Implant Coating for Enhanced Bone Growth

"Orthobiologics" provides an improved method of treating fractures and other bone defects. This therapy employs inductive molecules, such as bone morphogenetic protein-2 or bone morphogeneti...
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William Murphy, Jae Sam Lee, Mark Markel, Ben Graf | P07031US

Technology

Calibrated Drill Sleeve Also Protects Soft Tissue

Drills are commonly used during orthopedic surgery to place screws that allow fixation of fractured bones. One problem that surgeons face while drilling is the overlying soft tissue becoming entangled...
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Kenneth Xu, Austin Crow, Josh Kolz, Sarah Sandock, John Renfrew | P120364US01

Technology

Microfluidic Device for Drug Delivery

Oral ingestion of pharmaceuticals is considered the safest, most convenient and most economical method of administering drugs. However, many pharmaceuticals cannot be delivered orally because they are...
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David Beebe, Michael MacDonald, David Eddington, Glennys Mensing | P04240US

Technology

Click Chemistry-Based Multi-Enhanced Biomaterials Help Heal Wounds

Wound healing is a complex and dynamic process of rebuilding skin and tissue. Chronic or impaired wounds result when tissues fail to progress through the necessary stages of healing. This is a signifi...
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Weiyuan John Kao, Yao Fu | P100330US02

Technology

Biodegradable, Biocompatible Tannin-Chitosan Composites for Therapeutic Applications

Chitosan is a soluble biopolymer derived from chitin, which is a structural element in the shell of marine arthropods. Chitosan is used in water processing and agriculture. It also is used...
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Jess Reed, Christian Krueger, Sergio Madrigal-Carballo | P09128US02

Technology

Bone Tissue Regeneration System That Provides Spatial and Temporal Control Over the Release of Growth Factors

A fracture requiring orthopedic treatment occurs approximately every 14 seconds in the United States. Musculoskeletal conditions cost an estimated $254 billion each year in the United States, an...
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William Murphy, Mark Markel, Ben Graf, Yan Lu, Jae Sung Lee | P09200US

Technology

Microneedle-Based Device for Steady, Autonomous Delivery of Liquid Drugs Like Insulin

Oral ingestion of pharmaceuticals currently is considered the safest, most convenient and most economical method of drug administration. However, oral delivery of many pharmaceuticals is not possible ...
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David Beebe, Benjamin Moga, Kent Chase, Garrick Smith, Jake Myre | P100100US01

Technology

Bioactive and Biocompatible Copolymers for Use in Medical Implants

Many human diseases and conditions can be treated by implanting devices within the body. However, these devices may be rejected by the body’s immune system or “fouled” by the accumul...
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Kristyn Masters, Wendy Crone, Fangmin Xu | P07185US