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Liquid crystals, soft materials comprised of assemblies of organic molecules that exhibit long-range order at the five to 100 nanometer length scale, find widespread application in consumer goods rang...
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Mahesh Mahanthappa, Gregory Sorenson, Keiva Coppage | P120009US01

Technology

New Compounds for Treating High Blood Cholesterol and More

Indole is one of the most abundant heterocycles in pharmaceuticals and bioactive natural products, such as indometacin, a non-steroid anti-inflammatory drug, and vincristine, a natural product used to...
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Weiping Tang, Xiaoxun Li | P150140US02

Technology

Boron- and Nitride-Containing Catalysts for Oxidative Dehydrogenation of Small Alkanes and Oxidative Coupling of Methane

C3 and C4 olefins such as propene are key starting materials in the plastics and chemical industry. The main method for producing these critical building blocks is a petrochemical process called steam...
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Ive Hermans, Joseph Grant, Carlos Carrero Marquez, Alessandro Chieregato, Juan Venegas | P150387US02

Technology

Synthesizing Natural Products to Treat High Blood Cholesterol

Weiping Tang, Dongxu Shu, Gabrielle Winston-McPherson, Xiaoxun Li | P150023US03

Technology

More Stable, Efficient Photocatalysts for Reducing Small Molecules

The reduction of small molecules such as nitrogen and carbon dioxide is extremely difficult because one-electron reduction processes often involve high-energy intermediates. Nitrogen reduction usually...
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Robert Hamers, Di Zhu, Marco Torelli | P150202US01

Technology

Palladium-Based Catalysts Herald Greater Efficiency of Alcohol Oxidation to Esters and Acids

Converting hydrocarbon feedstocks like shale natural gas into higher value fine chemicals and pharmaceuticals requires the oxidation of various functional groups. However, oxidizing alcohols to carbox...
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Shannon Stahl, Adam Powell, Thatcher Root, David Mannel, Maaz Ahmed | P130355US02

Technology

Fast and Efficient Catalytic Metathesis of Secondary Amides for the Synthesis of Novel Molecules

Dynamic covalent chemistry (DCC) offers a powerful approach for the controlled synthesis of organic molecules with interesting structures and/or properties. It describes reactions that involve th...
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Samuel Gellman, Denis Kissounko, Shannon Stahl, Christen Bell | P06411US

Technology

“Green” Catalytic Systems for Solvent-Free Alcohol Oxidations

Catalysts for organic chemical transformations, in particular those used for alcohol oxidations, are considered to be valuable commodities for the bulk, fine chemical as well as pharmaceutical industr...
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Robert McGaff | T150040US03

Technology

Gemini Surfactant LLC Membranes from Thiol-Ene Polymerizations

Lyotropic liquid crystal (LLC) assemblies are useful for highly selective chemical separations, such as water desalination and selective ion-transporting membranes. Bicontinuous cubic LLC assemblies a...
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Mahesh Mahanthappa, James Jennings | P150015US01

Technology

Phosphine Ligands Made Cheaper, Better

Enantiomers are pairs of compounds that have the same chemical formula but different spatial structures (like your left and right hand, they are non-superimposable mirror images of each other). This i...
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Jennifer Schomaker, Robert Grigg, Ryan Van Hoveln | P130268US02

Technology

Selective Conversion of Lignin into Simple Aromatic Compounds

Lignin is a major component of non-edible biomass (15-30 percent by weight; 40 percent by energy). It is a cheap byproduct of pulp and biofuel production and is one of the few naturally occurring sour...
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Shannon Stahl, Alireza Rahimi | P130104US01

Technology

Crosslinkable Gemini Dicarboxylate Surfactant LLCs and Their Membranes

Aqueous lyotropic liquid crystal (LLC) assemblies are useful for highly selective chemical separations, such as water desalination and selective ion-transporting membranes. LLCs are formed in water wh...
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Mahesh Mahanthappa, Gregory Sorenson | P120048US02

Technology

Generating Medical Isotopes with Safer Vessel and Materials

Medical isotopes are valuable healthcare tools for patient imaging and disease treatment. Yet most radioisotopes used in medicine are produced in nuclear reactors, which are complex, generate high vol...
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Gregory Piefer, Thad Heltemes, Ross Radel, Eric Van Abel | P120047US01

Technology

Easier, More Flexible Synthesis of Therapeutic and Promising Compounds

Many pharmaceuticals and other biologically active molecules contain chemical sequences called triads that are challenging to prepare in the laboratory. Specifically, triads are three or more contiguo...
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Jennifer Schomaker, Luke Boralsky, John Hershberger, Jared Rigoli, Christopher Adams | P110299US02

Technology

Streamlined Scheduling for Large-Scale Chemical Production

In chemical manufacturing, a production system may receive and process raw materials in multiple steps, with each step or task associated with a certain procedure or tool. Ideally, each step is schedu...
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Christos Maravelias, Sara Velez, Arul Sundaramoorthy | P120218US01