Fluorescent microscopes, including wide-field, confocal and super-resolution, are widely used instruments in a variety of research fields but require routine calibration and maintenance. Calibration r...
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Soft materials are everywhere. In many applications, valuable information about the strength of these materials enables more precise control in everything from cutting and processing soft foods to des...
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The three-dimensional structure of proteins can be studied in solution using various methods of covalent and noncovalent labeling in which the readout is accomplished by mass spectrometry (MS). These ...
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A UW-Madison researcher has developed an improved method and associated system for coherent multidimensional spectroscopy (CMDS). CMDS is based on the formation of Schrӧdinger cat states by exciting ...
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Single particle cryo-electron microscopy (cryo-EM) is a powerful tool for providing 3-D structural information on non-crystalline specimens. Cryo-EM approaches atomic level resolution, enabling many n...
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Single particle cryo-electron microscopy is a powerful tool for providing 3-D structural information on non-crystalline specimens. Cryo-EM approaches atomic level resolution, enabling many new biologi...
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Single particle cryo-electron microscopy (cryo-EM) is a powerful tool for providing 3-D structural information on non-crystalline specimens. Cryo-EM approaches atomic level resolution, enabling many n...
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A UW researcher has developed a digital system for controlling pressure oscillations within a wellbore, as well as associated monitoring equipment and analysis codes. The equipment includes a wellhead...
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Detecting chemical and biological agents at low levels is important in military applications, drug enforcement, airport security and environmental monitoring.  A variety of devices and methods curren...
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Light microscopy is a well-established tool to study protein dynamics and protein functions in fixed and living cells. One limitation of light microscopy is that its diffraction limit (optical resolut...
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Proteomics is a relatively new discipline that is a large scale study of proteins. It includes systematically identifying the sequence, characterizing the structure and evaluating the function of all ...
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Surface mounted and exposed sensors are used in objects commonly found in a modern society that range from simple temperature monitors to complex airbag ejection systems. But sensors located on the su...
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Cellular interactions and signaling in multicellular organisms involve complex pathways that can be difficult to study when using macroscale in vitro culture systems, in part because traditional macro...
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Protein characterization has become an integral part of modern biology, even inspiring a new discipline known as proteomics, or the classification of proteins based on the genome of an organism.  MS ...
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Real-time vibration sensing is important in a variety of applications in industry, health care, and environmental monitoring. For example, vibration monitoring can assist in the prediction of natural ...
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UW-Madison researchers have developed improvements to the optical sensor described in P230334US01 that can better measure dissolved impurities in high temperature molten salt systems. These improvemen...
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Microfluidic devices have been proven useful for exploring a variety of biological questions, such as how cell-derived soluble signaling affects cellular processes. Passive pumping is a common method ...
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Computer chips, composed of silicon (Si) semiconductors, store and transmit information as electrons.  The negative charge on electrons, however, hinders the speed with which information can be trans...
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UW-Madison researchers have developed an optical sensor that can be used to monitor trace impurities in molten salts, including FLiNaK, Flibe, MgCl2, nitrates, and carbonates. This optical impurity pr...
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Researchers from UW-Madison and University of Puerto Rico – Mayaguez have created an improved droplet-based LC sensors for the selective detection of analytes. The researchers improved upon earlier ...
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UW-Madison (and University of Cambridge) researchers have developed an improved system for measuring the mass of single molecules (SMs). Their system leverages Fabry-Pérot (FP) microcavities for cavi...
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Although current microscopic optical systems are highly sensitive, they are generally bulky and expensive, and most have a severely limited field of vision. One alternative is adaptive microlenses tha...
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UW-Madison researchers have designed an improved infrared absorber using significantly larger, micron-sized (>1000 nm), metallic cuboids that exhibit improved field coupling for enhanced infrared s...
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UW-Madison researchers have developed a microfluidic flow cell for EM sample grid preparation. The two-piece device was designed so that EM substrates (grids or disks) could be placed within a central...
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