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224 Results for 'Analytical Instrumentation, Methods & Materials'
PAGE 3 OF 9
Technology
LONG DISTANCE WIRELESS RADIO TAG WITH RF ENERGY HARVESTING
The range of passive RFID tags is constrained by three factors. The first is that the reflected energy to the reader rapidly decreases with distance between the reader and the RFID tag both with respe...
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Bhuvana Krishnaswamy, Yaman Sangar, Kai Pederson | P230128US02
Technology
APPARATUS AND METHOD FOR DIRECT NITRATE SENSING IN SOIL
Nitrate is a nutrient that helps plants grow, but too much of it can be harmful. Nitrate monitoring can be used to reduce the amount of fertilizer needed, which is better for the environment and can ...
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Joseph Andrews, Jingyi Huang, Aatresha Biswas | P230143US01
Technology
DIAZOBUTANONE LINKER-ASSISTED HIGH-THROUGHPUT QUANTITATIVE ANALYSIS FOR PHOSPHATE AND SULFATE CONTAINING LIPIDS
UW-Madison researchers have developed a novel linker, diazobutanone, for functionalization of phosphate and sulfate containing lipids. The linker, made via a relatively simple two-step process, includ...
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Lingjun Li, Ting-Jia Gu, Peng-Kai Liu | P230446US01
Technology
Fluorescent Indicator of Lithium Ions
UW-Madison researchers have developed a novel profluorophore that binds to lithium ions with high specificity, inducing a fluorescent signal. The fluorescent indicator can be seamlessly integrated int...
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Randall Goldsmith | P150162US02
Technology
MICROFLUIDIC DEVICE AND METHOD FOR GENERATING A SKIN CONSTRUCT
Research into new therapies for skin diseases is challenging for a number of reasons. As is known, skin cells are exposed to both atmospheric air and liquids within the body. However, conventional cel...
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Jose Ayuso, Catherine Reed McBain, Seth Zima, Rithvik Turaga, Vijayasaradhi Setaluri | P230351US01
Technology
Volume-Free Reagent Addition and Exclusion-Based Sample Preparation Enables Multistep Microscale Assays
Liquid handling is a critical step in biological assays and typically includes either a reagent addition or solution exchange process. However, it’s challenging to manipulate samples on the microsca...
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David Beebe, Joshua Lang, Duane Juang, Scott Berry, Tamara Rodems | P190228US02
Technology
High-Efficiency Modeling of Three-Dimensional Lumens
Lumens are tubular structures pervasive throughout all body systems. Typical in vitro cell models used by pharmaceutical industries lack the dimensional complexity necessary to mimic lumen structures ...
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Patrick McMinn, David Beebe | P190284US01
Technology
ENERGY HARVESTING MULTISENSOR WILDFIRE MONITORING SYSTEM
Wildfires occur naturally in many ecosystems worldwide; however, the frequency of wildfires has increased in recent years. The United States National Interagency Fire Center reports that the total bur...
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Umit Ogras, Yigit Tuncel, Toygun Basaklar | P240049US01
Technology
A NONIONIC, REDOX-CLEAVABLE SURFACTANT FOR MASS SPECTROMETRY-BASED PROTEOMICS AND STRUCTURAL BIOLOGICAL APPLICATIONS
UW-Madison researchers have developed a nonionic cleavable surfactant (NCS) for mass spectrometry (MS)-based proteomics and analysis. Specifically, NCS was designed and synthesized to include a cleava...
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Ying Ge, Kyle Brown, Song Jin, Morgan Gugger | P220246US02
Technology
NAVIGATION SYSTEM USING CELESTIAL RADIO EMISSIONS
A UW-Madison researcher has developed a celestial guidance system that uses radio imaging of celestial bodies including the galactic plane received by an interferometric antenna array to provide robus...
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Kael Hanson | P220345US01
Technology
MULTIPLEXED DILEU-BIOTIN-AZIDE (DBA) TAG ENABLED ISOBARIC TANDEM ORTHOGONAL PROTEOLYSIS ACTIVITY-BASED PROTEIN PROFILING (ISOBOP-ABPP) PLATFORM FOR HIGH-THROUGHPUT QUANTITATIVE PAN-PTM ANALYSIS
UW-Madison researchers have developed a set of novel isobaric chemical tags, DiLeu-Biotin-Azide (DBA), that could be useful in proteomics, particularly quantification of post translational modificatio...
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Lingjun Li, Miyang Li, Min Ma | P220286US02
Technology
SOIL GAS-FLUX MEASUREMENT SYSTEM
Soil produces or consumes gases such as carbon dioxide, methane, nitrous oxide, ammonia, and oxygen through normal biological and geological processes. Current soil gas-flux measurement systems are ex...
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Bhuvana Krishnaswamy, Jingyi Huang, Francisco Arriaga, Christian Martinez, Hendri Winanto, Adam Nygard | P230171US01
Technology
BEAD-ENABLED, EFFICIENT, AND RAPID MULTI-OMIC SAMPLE PREPARATION FOR MASS SPECTROMETRY ANALYSIS
UW-Madison researchers developed a new process for preparing proteins, lipids, and metabolites for MS-based multi-omics. The process is based on an monophasic extraction solvent (e.g., n-butanol) that...
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Joshua Coon, Laura Muehlbauer, Katherine Overmyer, Annie Jen, Yunyun Zhu | P220205US02
Technology
Development of a Novel Mass Spectrometry-Based Method for Simultaneous Qualitative and Quantitative Protein Citrullination Analysis of Complex Biological Samples
UW-Madison researchers have developed a novel mass spectrometry (MS)-based method for simultaneous qualitative and quantitative protein citrullination analysis from biological and clinical samples. Th...
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Lingjun Li, Yatao Shi, Zihui Li | P190302US02
Technology
COHERENT LIGHT SOURCE BASED ON COLLECTIVE SPONTANEOUS EMISSION
Coherent light sources, in which the photons have highly matched frequencies and phases, are commonly produced by lasers. In a laser, the atoms of a laser medium are stimulated to excite the electrons...
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Deniz Yavuz, Mark Saffman, David Gold, Thad Walker | P220098US02
Technology
Matrices and systems for preservation of biomolecules in vacuum
UW-Madison and Morgridge Institute researchers have identified developed an improved method for depositing samples on electron microscopy (EM) grids. The technology leverages a modified mass spectrome...
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Joshua Coon, Michael Westphall, Kenneth Lee, Austin Salome, Timothy Grant, Jean Lodge | P220041WO01
Technology
CELL-BASED DNA SENSORS AND METHODS OF USING SAME
UW-Madison researchers have developed cell-based DNA sensors to achieve easy, accurate, and cost-effective detection of pathogens. Using synthetic biology, the inventors engineered the naturally compe...
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Ophelia Venturelli, Yu-Yu Cheng, Zhengyi Chen | P210411US02
Technology
A NOVEL STRATEGY ENABLED BY A PHOTO-CLEAVABLE SURFACTANT FOR EXTRACELLULAR VESICLE PROTEOMICS
Building off of their prior discovery (Photo-Cleavable Surfactants P180335US02), UW-Madison researchers disclose an improved method for exosome proteomics. The method leverages the researchers’ phot...
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Ying Ge, Song Jin, Kyle Brown, Kevin Buck | P220113US02
Technology
LIQUID CRYSTAL-INFUSED SLIPPERY ANTI-FOULING SURFACES
Building off their earlier work with LC-infused multilayer films, the inventors developed a method for directly infusing LCs into porous PTFE membranes. The resulting materials have desirable charac...
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David Lynn, Harshit Agarwal | P210229US02
Technology
DEVICE AND METHOD FOR CONTROLLING AND CONFIGURING THE SPACIAL AND TEMPORTAL EVOLUTION OF A GRADIENT IN A MICROFLUIDIC ENVIRONMENT
UW-Madison researchers have developed a well-plate for cell culture that allows the user to finely define the location and temporal profile of multiple gradients including oxygen, nutrients, chemoattr...
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David Beebe, Jose Ayuso, Maria Virumbrales Munoz, Cristina Sanchez de Diego | P220125US01
Technology
RAPID ESTIMATION OF A SOIL-WATER RETENTION CURVE USING VISIBLE-NEAR INFRARED SPECTROSCOPY
UW-Madison researchers have developed improved methods and systems for characterizing soil using visible-near-infrared spectroscopy (vis-NIRS) data. Combining their spectrographic data with additional...
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Jingyi Huang, Zampela Pittaki-Chrysodonta, Alfred Hartemink | P210177US02
Technology
ELECTROMECHANICAL FORCE SENSOR BASED ON EXTREMA DEGENERACY POINT WITH NONLINEAR RESPONSE
UW-Madison researchers and collaborators from Wesleyan University have shown, using an exceptional point (EP)-based PT-symmetric electromechanical accelerometer, that increases in technical noise can ...
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Ramathasan Thevamaran, Jizhe Cai, Tsampikos Kottos, Fred Ellis, Rodion Kononchuk | P220050US01
Technology
ALKALI METAL OPTICAL CLOCK
UW researchers have invented a Cesium Lattice Optical Clock (CLOC) for high performance and simple operation in a compact form factor. The novel design uses a “forbidden” optical transition in Cs ...
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Mark Saffman, Shimon Kolkowitz, Arjav Sharma | P220217US01
Technology
SYSTEMS AND METHODS FOR DETERMINING MECHANICAL PROPERTIES IN SUBSURFACE FORMATIONS
A UW-Madison researcher has developed a method for predicting subsurface mechanical properties using distributed strain measurements obtained from applied perturbations. The method relies on model cha...
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Jesse Hampton | P190275WO01
Technology
UW-Madison researchers, working in collaboration with researchers from Cornell, developed metal-oxide based liquid crystal (LC) sensors for monitoring catalytic reactions. The inventors used a previou...
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Emmanouil Mavrikakis, Jake Gold, Trenton Wolter, Nicholas Abbott, Nanqi Bao, Huaizhe Yu, Ayushi Tripathi | P220044US01