In 2016, approximately 135,000 new cases of colon and rectal cancers will be diagnosed and nearly 50,000 will die from this disease, making it the one of the most common causes of cancer related death...
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The importance of T cells in immunotherapy is driving the development of technologies to better characterize T cells and improve therapeutic efficacy. One specific objective is assessing antigen-induc...
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A new cancer treatment being studied at a few major centers including UW Health is CAR T (Chimeric Antigen Receptor T cell) therapy. CAR T therapy uses a patient's own cells and 'reengineers' them to ...
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Bacterial contamination is a major risk in biologics manufacturing and the presence of endotoxin, an outer membrane component of Gram-negative bacteria, is vigorously tested for in protein and DNA/RNA...
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Cancer treatment planning remains an ongoing challenge to oncologists and patients alike, with each cancer being genetically unique and requiring personalized approaches. Greater outcome success will ...
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An otoscope is a classic handheld medical device that allows doctors to look into the ear canal and tympanic membrane (eardrum). It is used to diagnose ear infections, membrane ruptures and foreign ob...
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The catabolic state refers to the condition where the body uses stores of carbohydrates, amino acids or fats as a source of energy for maintenance. The catabolic state may be induced by infection, dis...
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Prostate cancer is the second most common cancer in American men, causing more than 27,000 deaths every year. An estimated one man in seven will be diagnosed with prostate cancer during his lifetime. ...
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Approximately 15 million Americans suffer from a swallowing disorder (dysphagia). People with acid reflux, a neurological disorder or cancer of the head and neck are particularly at risk. The leading ...
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Compact solid-state LED/LD (light-emitting diode) light sources are by their nature near-point sources. Applications that take advantage of these highly efficient, spectrally engineered light sources ...
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Time-frequency analysis involves detecting when oscillations of certain frequencies turn on and off. This kind of analysis is useful in nearly every field of science and engineering. The traditional a...
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Coronary heart disease is a leading cause of morbidity and mortality in the United States. A key challenge facing the cardiology community is the identification of high-risk individuals who would bene...
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Fiber optic probes can be used for spectroscopic measurement of tissue. A fiber optic tube emits light on one side of the tissue that is absorbed and measured on the other side by fiber optic detector...
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Light-based diagnostics are used to create images of human tissue to detect the development of diseases like cancer. The popularity of light-based diagnostics is growing due to their non-intrusive nat...
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Epileptogenesis, or the occurrence of spontaneous seizures, is considered to be a learned response due to brain plasticity.  The development of the condition requires circuits in the brain to pos...
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Diffuse reflectance spectroscopy can be used to measure tissue absorption and scattering, which reflect the intrinsic physiological and structural properties of tissue respectively. This technique can...
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The early detection of disease or malignancy can greatly increase the probability of full recovery, especially in the case of cancers.  Optical diagnostic techniques, such as diffuse reflectance ...
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Phsyicians often use microscopic visual inspection followed by biopsy to detect cancer; however, this method is limited in many ways. Optical techniques are a promising alternative that allows clinici...
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Optical imaging techniques play a pivotal role in detecting disease, injury and other disorders at an early stage and monitoring progression or remission after treatment. Images are generated by detec...
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Skin cancer detection is typically identified via standard visual inspection. Skin patches with asymmetrical outlines, irregular borders, mottled color or a diameter greater than six millimeters are a...
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