Wisconsin Alumni Research Foundation

Diagnostics & Biomarkers
Diagnostics Biomarkers
NOVEL AUTO-ANTIBODIES AND METHOD TO DETECT SJÖGREN’S DISEASE
WARF: P220234WO01

Inventors: Sara McCoy, Miriam Shelef, Michael Newton, Zihao Zheng


The Invention
A UW-Madison researcher has developed a new diagnostic assay for Sjogren's syndrome, based on her discovery of novel autoantibodies relevant to the disease process. Using whole peptidome array technology, the inventor has identified top candidate novel autoantibodies that can be found in patient serum and used to diagnose patients who are SSA negative (instead of a lip biopsy). Interestingly, she found that a panel of 8 autoantibodies provided 30% sensitivity and 100% specificity in White/Hispanic patients, and one of those autoantibodies provided 36% sensitivity and 100% specificity in Asian patients. 
Additional Information
For More Information About the Inventors
For current licensing status, please contact Jennifer Gottwald at [javascript protected email address] or 608-960-9854

WARF