Search Results
6 Results for 'Biologics'
PAGE 1 OF 1
Technology
Targeting Cancer Therapeutics and Diagnostics with Camelid Antibodies That Bind FAP
Fibroblast Activation Protein (FAP) is expressed in 90% of all solid tumors, making it an attractive target in cancer. Current small molecules targeting FAP clear from the system too rapidly, and FAP-...
Learn More
Learn More
Aaron LeBeau, Joseph Gallant | P230173US01
Technology
GENERATION OF NEXT GENERATION RECOMBINANT AAV GENE THERAPY VECTORS THAT ADOPT 3D CONFORMATION
UW-Madison researchers have developed approaches to improve recombinant AAV gene therapy vectors (rAAV) therapies by improving their expression in target cells. The inventors have discovered that the ...
Learn More
Learn More
Kinjal Majumder, Clairine Larsen | P220260US02
Technology
SIRPα Inhibited Macrophages and Neutrophils and Uses Thereof
UW-Madison researchers have developed methods for generating SIRPα-KO macrophages with superior anti-tumor activity, and SIRPα-knockout neutrophils with superior anti-bacterial and anti-tu...
Learn More
Learn More
Igor Slukvin, Portia Smith, Aditi Majumder, Anna Huttenlocher, David Bennin | P220110US02
Technology
pH-Responsive Nanoparticle For Delivery Of Ribonucleoproteins
UW researchers have developed a polymeric nanoparticle to package and deliver a CRISPR/Cas protein/guide RNA complex and, optionally, a single stranded DNA repair template into cells for gene therapy....
Learn More
Learn More
Shaoqin Gong, Ruosen Xie, Xiuxiu Wang | P210402WO01
Technology
Anti-CD40 Single-Chain Variable Fragment And Human IL-21 Fusion Protein (CD40SCFV-IL-21)
UW-Madison researchers have developed a novel fusion protein for inducing Breg cell formation and a method for transforming any human B cell into an IL10-competent, functional Breg cell ex vivo at sca...
Learn More
Learn More
Jacques Galipeau, Andrea Pennati, Shala Yuan | P210323WO01
Technology
DERIVATION OF HEPATOCYTES AND HEMATOPOIETIC PROGENITORS FROM HUMAN EMBRYONIC STEM CELLS
The inventors have developed a novel system for co-differentiation of hepatocytes and hematopoietic progenitors from human embryonic stem cells (ES cells) that mimics a late fetal liver undergoing hem...
Learn More
Learn More
James Thomson, Srikumar Sengupta | P210190US02