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4 Results for 'Biologics'
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Technology
SIRPα Inhibited Macrophages and Neutrophils and Uses Thereof
UW-Madison researchers have developed methods for generating SIRPα-KO macrophages with superior anti-tumor activity, and SIRPα-knockout neutrophils with superior anti-bacterial and anti-tu...
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Igor Slukvin, Portia Smith, Aditi Majumder, Anna Huttenlocher, David Bennin | P220110US02
Technology
pH-Responsive Nanoparticle For Delivery Of Ribonucleoproteins
UW researchers have developed a polymeric nanoparticle to package and deliver a CRISPR/Cas protein/guide RNA complex and, optionally, a single stranded DNA repair template into cells for gene therapy....
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Shaoqin Gong, Ruosen Xie, Xiuxiu Wang | P210402WO01
Technology
Anti-CD40 Single-Chain Variable Fragment And Human IL-21 Fusion Protein (CD40SCFV-IL-21)
UW-Madison researchers have developed a novel fusion protein for inducing Breg cell formation and a method for transforming any human B cell into an IL10-competent, functional Breg cell ex vivo at sca...
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Jacques Galipeau, Andrea Pennati, Shala Yuan | P210323WO01
Technology
DERIVATION OF HEPATOCYTES AND HEMATOPOIETIC PROGENITORS FROM HUMAN EMBRYONIC STEM CELLS
The inventors have developed a novel system for co-differentiation of hepatocytes and hematopoietic progenitors from human embryonic stem cells (ES cells) that mimics a late fetal liver undergoing hem...
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James Thomson, Srikumar Sengupta | P210190US02