Many drugs that are potentially efficacious for treating diseases, such as cancer, have limited usefulness because they are relatively insoluble. Preparing these drugs in an amorphous, or “glass...
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Development of most tissue types involves a complex interplay of multiple growth factors in well defined locations, leading to controlled differentiation of precursor cells into mature, tissue-specifi...
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Thin films and coatings that allow the sustained release of DNA from surfaces play an important role in the development of localized approaches to gene therapy. For example, polymer-coated intravascul...
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Under physiological conditions, bone tissue regeneration involves a complex interplay of multiple biologically active molecules and stem cells. The molecules are often presented sequentially in cascad...
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Dendritic cells play an important role in the process of initiating immune response. They are present in small quantities in tissues, such as skin and lung, that are in contact with the external envir...
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Oral ingestion of pharmaceuticals is considered the safest, most convenient and most economical method of drug administration.  However, many therapeutic drugs cannot be delivered orally because ...
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Biodegradable scaffolds with highly interconnected pores are potentially useful in tissue engineering. A rigid, highly porous platform could be used to guide growth in tissues such as bone, cartilage ...
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Even though therapeutic compounds have been developed for neurologic disorders, such as Alzheimer’s disease, these conditions remain difficult to treat, largely because of the blood-brain barrie...
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Many drugs that are potentially efficacious for treating diseases such as cancer have limited usefulness because they are relatively insoluble and/or toxic. Polymeric micelles can serve as vehicles fo...
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Many drugs that are potentially efficacious for treating diseases, such as cancer, have limited usefulness because they are relatively insoluble. Preparing these drugs in an amorphous, or “glass...
Learn More