Wisconsin Alumni Research Foundation

Animals, Agriculture & Food
Animals Agriculture Food
Natural Feed Additive Combats Gastrointestinal Infection in Livestock and Poultry
WARF: P120128US01

Inventors: Mark Cook, Jordan Sand

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a method of maintaining growth in protozoan-infected animals by administering interleukin-10 peptides and antibodies.
Reaping billion dollar losses every year, coccidiosis is a common protozoan infection of agricultural animals that targets the digestive system. Its symptoms include weight loss, diarrhea and suppressed growth.

Drugs have been developed to treat the disease, but are being phased out in markets in Europe and Asia due to potential hazards to both animals and humans. The emergence of resistant strains also has spurred interest in fresh tactics. Vaccines are one alternative, but they take several weeks to become effective and may undermine animal growth. A need exists for a safe solution acceptable worldwide.
The Invention
UW–Madison researchers have developed a method for treating and maintaining healthy growth in animals infected with gastrointestinal protozoa using interleukin-10 (IL-10) peptides and antibodies.

Incorporating standard techniques, blood serum or eggs produced from hens vaccinated with IL-10 peptide vaccines can be obtained and dried to form an antibody-containing powder. The egg, yolk or serum powder may be added to animal feed in an appropriate amount to transfer the antibodies.
  • Producing agricultural feed
  • Raising poultry, cow, pig, sheep, fish and other livestock
Key Benefits
  • Alleviates growth and weight depression caused by coccidiosis
  • None of the drawbacks of drugs/vaccines
  • Method has potential to prevent or treat all gastrointestinal protozoan infections.
  • Satisfies consumer preferences
Stage of Development
The development of this technology was supported by WARF Accelerator. WARF Accelerator selects WARF's most commercially promising technologies and provides expert assistance and funding to enable achievement of commercially significant milestones. WARF believes that these technologies are especially attractive opportunities for licensing.
Additional Information
For current licensing status, please contact Emily Bauer at [javascript protected email address] or 608-960-9842