Wisconsin Alumni Research Foundation

Medical Devices
Medical Devices
Wavy Multi-Component Vascular Grafts With Biomimetic Mechanical Properties, Antithrombogenicity, And Endothelial Cell Affinity
WARF: P180253US02

Inventors: Lih-Sheng Turng, Haoyang Mi

The Invention
Disclosed herein are novel wavy, multi-component vascular grafts (WMVGs) with a wavy inner layer of rigid biopolymer fibers and an outer layer of elastic biopolymer fibers and a method for preparing WMVGs via electrospinning using a special assembled collector. The fabricated WMVGs closely mimic the non-linear tensile stress-strain relationship of native blood vessels and showed sufficient mechanical strength needed for implantation.
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